Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLHL24
  • Mouse genes Klhl24
  • Rat genes Klhl24
  • Zfish genes klhl24a,klhl24b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klhl24

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KLHL24	IPI	UniProtKB:P02533	Human	PMID:27798626
Molecular Function	GO:0005515	protein binding	KLHL24	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL24	IPI	UniProtKB:Q53G59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL24	IPI	UniProtKB:Q8NEY4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL24	IPI	UniProtKB:Q14145	Human	PMID:35044719
Cellular Component	GO:0005912	adherens junction	KLHL24	IDA		Human	PMID:27889062
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	KLHL24	IMP		Human	PMID:27798626
Cellular Component	GO:0005737	cytoplasm	KLHL24	IDA		Human	PMID:27889062
Cellular Component	GO:0030057	desmosome	KLHL24	IDA		Human	PMID:27889062
Biological Process	GO:0007507	heart development	klhl24a	IMP	ZFIN:ZDB-MRPHLNO-191021-2	Zfish	PMID:30715372
Biological Process	GO:0007507	heart development	klhl24a	IMP	ZFIN:ZDB-MRPHLNO-191021-3	Zfish	PMID:30715372
Biological Process	GO:0045109	intermediate filament organization	KLHL24	IMP		Human	PMID:27889062
Biological Process	GO:0051865	protein autoubiquitination	KLHL24	IMP		Human	PMID:27798626
Biological Process	GO:0016567	protein ubiquitination	KLHL24	IDA		Human	PMID:27798626

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern