Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLB
  • Mouse genes Klb
  • Rat genes Klb
  • Zfish genes klb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017134	fibroblast growth factor binding	KLB	IPI	UniProtKB:O95750	Human	PMID:18829467
Molecular Function	GO:0017134	fibroblast growth factor binding	KLB	IPI	UniProtKB:Q9NSA1	Human	PMID:19117008
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	KLB	IPI	UniProtKB:P22455	Human	PMID:17627937
Molecular Function	GO:0005515	protein binding	KLB	IPI	UniProtKB:Q9NSA1	Human	PMID:19059246
Molecular Function	GO:0005515	protein binding	Klb	IPI	UniProtKB:P16092|UniProtKB:Q03142	Mouse	MGI:MGI:3709813|PMID:17452648
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:1861377	Mouse	PMID:18187602
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:95524	Mouse	PMID:18187602
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:95522	Mouse	PMID:18187602
Biological Process	GO:0008284	positive regulation of cell population proliferation	Klb	IGI	MGI:MGI:95522	Mouse	PMID:18187602
Biological Process	GO:0008284	positive regulation of cell population proliferation	Klb	IGI	MGI:MGI:95524	Mouse	PMID:18187602
Biological Process	GO:0008284	positive regulation of cell population proliferation	Klb	IGI	MGI:MGI:1861377	Mouse	PMID:18187602
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:95524	Mouse	PMID:18187602
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:95522	Mouse	PMID:18187602
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Klb	IGI	MGI:MGI:1861377	Mouse	PMID:18187602

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern