Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF22
  • Mouse genes Kif22
  • Rat genes Kif22
  • Zfish genes kif22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KIF22	IPI	UniProtKB:Q9H4H8	Human	PMID:18485706
Molecular Function	GO:0005515	protein binding	kif22	IPI	UniProtKB:D3JU52	Zfish	PMID:20143133
Cellular Component	GO:0000785	chromatin	Kif22	IDA		Mouse	PMID:11884614
Cellular Component	GO:0005829	cytosol	KIF22	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	KIF22	IDA		Human	PMID:18485706
Cellular Component	GO:0016607	nuclear speck	KIF22	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005819	spindle	Kif22	IDA		Mouse	PMID:11884614
Biological Process	GO:0007409	axonogenesis	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537
Biological Process	GO:0007420	brain development	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537
Biological Process	GO:0048592	eye morphogenesis	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537
Biological Process	GO:0051310	metaphase plate congression	KIF22	IMP		Human	PMID:18485706
Biological Process	GO:0051310	metaphase plate congression	KIF22	IMP		Human	PMID:25743205
Biological Process	GO:0007080	mitotic metaphase plate congression	KIF22	IMP		Human	PMID:15843429
Biological Process	GO:0007062	sister chromatid cohesion	KIF22	IMP		Human	PMID:15843429
Biological Process	GO:0001756	somitogenesis	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537
Biological Process	GO:0001966	thigmotaxis	kif22	IMP	ZFIN:ZDB-MRPHLNO-121210-5	Zfish	PMID:22566537

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern