Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KHDC3L
  • Mouse genes Khdc3
  • Rat genes Khdc3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Khdc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:A6NGQ2	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:P59047	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:Q9H808-1	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:A6NGQ2,UniProtKB:Q9H808	Human	PMID:26537248
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:P09874	Human	PMID:31609975
Molecular Function	GO:0005515	protein binding	KHDC3L	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Khdc3	IPI	UniProtKB:O88700|UniProtKB:Q61510|UniProtKB:Q9CWE6	Mouse	MGI:MGI:6467697|PMID:29125140
Molecular Function	GO:0005515	protein binding	Khdc3	IPI	UniProtKB:E9Q7G0|UniProtKB:P11103	Mouse	MGI:MGI:6716962|PMID:25936915
Molecular Function	GO:0005515	protein binding	Khdc3	IPI	PR:Q9R1M5	Mouse	PMID:18057100
Molecular Function	GO:0005515	protein binding	Khdc3	IPI	PR:Q66X22	Mouse	PMID:32413845
Molecular Function	GO:0005515	protein binding	Khdc3	IPI	PR:Q9R1M5	Mouse	PMID:18804437
Cellular Component	GO:0005938	cell cortex	Khdc3	IDA		Mouse	MGI:MGI:6296386|PMID:25208553
Cellular Component	GO:0005938	cell cortex	Khdc3	IDA		Mouse	MGI:MGI:6716962|PMID:25936915
Cellular Component	GO:0005938	cell cortex	Khdc3	IDA		Mouse	PMID:19376971
Cellular Component	GO:0005938	cell cortex	Khdc3	IDA		Mouse	PMID:18057100
Cellular Component	GO:0005938	cell cortex	Khdc3	IDA		Mouse	PMID:18804437
Cellular Component	GO:0005813	centrosome	Khdc3	IDA		Mouse	MGI:MGI:6716962|PMID:25936915
Cellular Component	GO:0005737	cytoplasm	KHDC3L	IDA		Human	PMID:25542835
Cellular Component	GO:0005739	mitochondrion	Khdc3	IDA		Mouse	MGI:MGI:6716962|PMID:25936915
Cellular Component	GO:0005634	nucleus	KHDC3L	IDA		Human	PMID:25542835
Cellular Component	GO:0005634	nucleus	KHDC3L	IDA		Human	PMID:31609975
Cellular Component	GO:0005634	nucleus	Khdc3	IDA		Mouse	MGI:MGI:6467697|PMID:29125140
Cellular Component	GO:0005634	nucleus	Khdc3	IDA		Mouse	MGI:MGI:6716977|PMID:33115731
Cellular Component	GO:0005634	nucleus	Khdc3	IDA		Mouse	MGI:MGI:6716962|PMID:25936915
Cellular Component	GO:0032991	protein-containing complex	KHDC3L	IDA		Human	PMID:26537248
Cellular Component	GO:0032991	protein-containing complex	Khdc3	IDA		Mouse	PMID:18057100
Cellular Component	GO:0032991	protein-containing complex	Khdc3	IDA		Mouse	PMID:18804437
Cellular Component	GO:0106333	subcortical maternal complex	KHDC3L	IDA		Human	PMID:25542835
Cellular Component	GO:0106333	subcortical maternal complex	KHDC3L	IDA		Human	PMID:26537248
Cellular Component	GO:0106333	subcortical maternal complex	Khdc3	IDA		Mouse	MGI:MGI:6467696|PMID:28992324
Cellular Component	GO:0106333	subcortical maternal complex	Khdc3	IDA		Mouse	MGI:MGI:3771666|PMID:18057100
Cellular Component	GO:0106333	subcortical maternal complex	Khdc3	IDA		Mouse	PMID:32413845
Biological Process	GO:0007015	actin filament organization	Khdc3	IMP		Mouse	MGI:MGI:6389592|PMID:31575650
Biological Process	GO:0051656	establishment of organelle localization	Khdc3	IMP		Mouse	MGI:MGI:6389592|PMID:31575650
Biological Process	GO:0090307	mitotic spindle assembly	Khdc3	IMP	MGI:MGI:3844604	Mouse	PMID:19376971
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	Khdc3	IMP	MGI:MGI:3844604	Mouse	PMID:19376971
Biological Process	GO:0043066	negative regulation of apoptotic process	Khdc3	IMP		Mouse	MGI:MGI:6716962|PMID:25936915
Biological Process	GO:1900006	positive regulation of dendrite development	Khdc3	IMP		Mouse	MGI:MGI:6716977|PMID:33115731
Biological Process	GO:2000781	positive regulation of double-strand break repair	Khdc3	IMP		Mouse	MGI:MGI:6716977|PMID:33115731
Biological Process	GO:2000781	positive regulation of double-strand break repair	Khdc3	IMP		Mouse	MGI:MGI:6467697|PMID:29125140
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	KHDC3L	IMP		Human	PMID:31609975
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	Khdc3	IMP		Mouse	MGI:MGI:6716962|PMID:25936915
Biological Process	GO:0040019	positive regulation of embryonic development	Khdc3	IMP		Mouse	MGI:MGI:6467697|PMID:29125140
Biological Process	GO:0050769	positive regulation of neurogenesis	Khdc3	IMP		Mouse	MGI:MGI:6716977|PMID:33115731
Biological Process	GO:0006468	protein phosphorylation	Khdc3	IMP	MGI:MGI:3844604	Mouse	PMID:19376971
Biological Process	GO:0032880	regulation of protein localization	KHDC3L	IMP		Human	PMID:31609975
Biological Process	GO:0032880	regulation of protein localization	Khdc3	IMP		Mouse	MGI:MGI:6467697|PMID:29125140
Biological Process	GO:0032880	regulation of protein localization	Khdc3	IMP		Mouse	MGI:MGI:6716962|PMID:25936915
Biological Process	GO:0031297	replication fork processing	Khdc3	IMP		Mouse	MGI:MGI:6467697|PMID:29125140

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern