Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDM7A
  • Mouse genes Kdm7a
  • Rat genes Kdm7a
  • Zfish genes kdm7aa,kdm7ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdm7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	KDM7A	IDA		Human	PMID:20023638
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	KDM7A	IDA		Human	PMID:20194436
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	KDM7A	IDA		Human	PMID:20023638
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	KDM7A	IDA		Human	PMID:20194436
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	KDM7A	IDA		Human	PMID:20622853
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	Kdm7a	IMP		Mouse	MGI:MGI:4437342|PMID:20194436
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	kdm7aa	IDA		Zfish	PMID:20194436
Molecular Function	GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	kdm7ab	IDA		Zfish	PMID:20194436
Molecular Function	GO:0051864	histone H3K36 demethylase activity	KDM7A	IDA		Human	PMID:20622853
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM7A	IDA		Human	PMID:20023638
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM7A	IDA		Human	PMID:20194436
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM7A	IDA		Human	PMID:20622853
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm7a	IMP		Mouse	MGI:MGI:4437342|PMID:20194436
Molecular Function	GO:0032454	histone H3K9 demethylase activity	kdm7aa	IDA		Zfish	PMID:20194436
Molecular Function	GO:0032454	histone H3K9 demethylase activity	kdm7ab	IDA		Zfish	PMID:20194436
Molecular Function	GO:0035575	histone H4K20 demethylase activity	KDM7A	IDA		Human	PMID:20622853
Molecular Function	GO:0005506	iron ion binding	KDM7A	IDA		Human	PMID:20023638
Molecular Function	GO:0035064	methylated histone binding	KDM7A	IDA		Human	PMID:20023638
Molecular Function	GO:0008270	zinc ion binding	KDM7A	IDA		Human	PMID:20023638
Cellular Component	GO:0005730	nucleolus	KDM7A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	KDM7A	IDA		Human	GO_REF:0000052
Biological Process	GO:0016570	histone modification	kdm7aa	IDA		Zfish	PMID:20194436|ZFIN:ZDB-PUB-100309-10
Biological Process	GO:0016570	histone modification	kdm7ab	IDA		Zfish	PMID:20194436|ZFIN:ZDB-PUB-100309-10
Biological Process	GO:0030901	midbrain development	kdm7aa	IMP		Zfish	PMID:20194436|ZFIN:ZDB-PUB-100309-10
Biological Process	GO:0030901	midbrain development	kdm7ab	IMP		Zfish	PMID:20194436|ZFIN:ZDB-PUB-100309-10
Biological Process	GO:0030901	midbrain development	kdm7aa	IGI	ZFIN:ZDB-MRPHLNO-100426-16,ZFIN:ZDB-MRPHLNO-100426-3	Zfish	PMID:20194436
Biological Process	GO:0030901	midbrain development	kdm7ab	IGI	ZFIN:ZDB-MRPHLNO-100426-15,ZFIN:ZDB-MRPHLNO-100426-19	Zfish	PMID:20194436
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Kdm7a	IMP		Mouse	MGI:MGI:4437342|PMID:20194436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern