Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDM5C
  • Mouse genes Kdm5c
  • Rat genes Kdm5c
  • Zfish genes kdm5c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdm5c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032453	histone H3K4 demethylase activity	KDM5C	IDA		Human	PMID:17320160
Molecular Function	GO:0032453	histone H3K4 demethylase activity	KDM5C	IMP		Human	PMID:28262558
Molecular Function	GO:0032453	histone H3K4 demethylase activity	Kdm5c	IDA		Mouse	PMID:23246292
Molecular Function	GO:0005515	protein binding	KDM5C	IPI	UniProtKB:Q13127	Human	PMID:17468742
Molecular Function	GO:0005515	protein binding	KDM5C	IPI	UniProtKB:P03122	Human	PMID:20133580
Molecular Function	GO:0008270	zinc ion binding	KDM5C	IDA		Human	PMID:27214403
Cellular Component	GO:0005829	cytosol	KDM5C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	KDM5C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	KDM5C	IDA		Human	PMID:18078810
Cellular Component	GO:0005634	nucleus	Kdm5c	IDA		Mouse	PMID:23246292
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Kdm5c	IDA		Mouse	MGI:MGI:5288521|PMID:21960634
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	kdm5c	IMP	ZFIN:ZDB-MRPHLNO-100427-14	Zfish	PMID:17320160
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	kdm5c	IMP	ZFIN:ZDB-MRPHLNO-100426-13	Zfish	PMID:17320160
Biological Process	GO:0009636	response to toxic substance	Kdm5c	IEP		Rat	PMID:23932495|RGD:9586022

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern