Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD7
  • Mouse genes Kctd7
  • Rat genes Kctd7
  • Zfish genes kctd7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KCTD7	IPI	UniProtKB:Q13618	Human	PMID:22748208
Cellular Component	GO:0005737	cytoplasm	KCTD7	IDA		Human	PMID:22748208
Cellular Component	GO:0005886	plasma membrane	KCTD7	IDA		Human	PMID:22748208
Cellular Component	GO:0005886	plasma membrane	Kctd7	IDA		Mouse	MGI:MGI:6107400|PMID:27742667
Biological Process	GO:0090461	intracellular glutamate homeostasis	KCTD7	IMP		Human	PMID:27742667
Biological Process	GO:0030007	intracellular potassium ion homeostasis	Kctd7	IMP		Mouse	MGI:MGI:6107400|PMID:27742667
Biological Process	GO:0060081	membrane hyperpolarization	Kctd7	IMP		Mouse	MGI:MGI:6107400|PMID:27742667
Biological Process	GO:0032411	positive regulation of transporter activity	Kctd7	IMP		Mouse	MGI:MGI:6107400|PMID:27742667

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern