Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNQ5
  • Mouse genes Kcnq5
  • Rat genes Kcnq5
  • Zfish genes kcnq5a,kcnq5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnq5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KCNQ5	IPI	UniProtKB:P51787	Human	PMID:24855057
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnq5	EXP		Rat	PMID:21666672|RGD:155230700
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnq5	IDA		Rat	PMID:21666672|RGD:155230700
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ5	IDA		Human	PMID:10787416
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ5	IDA		Human	PMID:11159685
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ5	IDA		Human	PMID:24855057
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ5	IMP		Human	PMID:28669405
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnq5	IDA		Mouse	PMID:15963599
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnq5	IMP		Rat	PMID:12032157|RGD:634683
Cellular Component	GO:0044305	calyx of Held	Kcnq5	IDA		Rat	PMID:17912742|RGD:155230792
Cellular Component	GO:0044305	calyx of Held	Kcnq5	EXP		Rat	PMID:21666672|RGD:155230700
Cellular Component	GO:0044305	calyx of Held	Kcnq5	IDA		Rat	PMID:21666672|RGD:155230700
Cellular Component	GO:0030118	clathrin coat	KCNQ5	IDA		Human	PMID:24855057
Cellular Component	GO:0005886	plasma membrane	KCNQ5	IDA		Human	PMID:10787416
Cellular Component	GO:0005886	plasma membrane	KCNQ5	IDA		Human	PMID:11159685
Cellular Component	GO:0042734	presynaptic membrane	Kcnq5	IDA		Rat	PMID:17912742|RGD:155230792
Cellular Component	GO:0042734	presynaptic membrane	Kcnq5	IDA		Rat	PMID:21666672|RGD:155230700
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNQ5	IDA		Human	PMID:10787416
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNQ5	IDA		Human	PMID:11159685
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNQ5	IDA		Human	PMID:10787416
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNQ5	IDA		Human	PMID:11159685
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNQ5	IMP		Human	PMID:28669405
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnq5	IDA		Mouse	MGI:MGI:3604268|PMID:15963599
Biological Process	GO:0006813	potassium ion transport	Kcnq5	IDA		Mouse	PMID:15963599
Biological Process	GO:0006813	potassium ion transport	Kcnq5	IMP		Rat	PMID:12032157|RGD:634683

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern