Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNQ4
  • Mouse genes Kcnq4
  • Rat genes Kcnq4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnq4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005267	potassium channel activity	Kcnq4	IDA		Rat	PMID:17021181|RGD:1600307
Molecular Function	GO:0005515	protein binding	KCNQ4	IPI	UniProtKB:Q8WWG9	Human	PMID:19687231
Molecular Function	GO:0005515	protein binding	KCNQ4	IPI	UniProtKB:P07900|UniProtKB:P08238	Human	PMID:23431407
Molecular Function	GO:0005515	protein binding	KCNQ4	IPI	UniProtKB:P11142|UniProtKB:P31689|UniProtKB:P31948|UniProtKB:Q9UNE7	Human	PMID:23431407
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnq4	IMP	MGI:MGI:3618993	Mouse	PMID:16437162
Cellular Component	GO:0005737	cytoplasm	Kcnq4	IDA		Rat	PMID:16775195|RGD:1600308
Cellular Component	GO:0043005	neuron projection	Kcnq4	IDA		Rat	PMID:16775195|RGD:1600308
Cellular Component	GO:0005886	plasma membrane	Kcnq4	IDA		Rat	PMID:17021181|RGD:1600307
Biological Process	GO:0042472	inner ear morphogenesis	Kcnq4	IMP	MGI:MGI:3618993	Mouse	PMID:16437162
Biological Process	GO:0032227	negative regulation of synaptic transmission, dopaminergic	Kcnq4	IMP		Rat	PMID:16775195|RGD:1600308
Biological Process	GO:0006813	potassium ion transport	Kcnq4	IMP	MGI:MGI:3618993	Mouse	PMID:16437162
Biological Process	GO:0006813	potassium ion transport	Kcnq4	IDA		Rat	PMID:17021181|RGD:1600307
Biological Process	GO:0007605	sensory perception of sound	Kcnq4	IMP	MGI:MGI:3618993	Mouse	PMID:16437162
Biological Process	GO:0007605	sensory perception of sound	Kcnq4	IEP		Rat	PMID:17021181|RGD:1600307

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern