Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNK5
  • Mouse genes Kcnk5
  • Rat genes Kcnk5
  • Zfish genes kcnk5a,kcnk5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnk5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015271	outward rectifier potassium channel activity	kcnk5b	IDA		Zfish	PMID:24453984
Molecular Function	GO:0005267	potassium channel activity	KCNK5	IDA		Human	PMID:9812978
Molecular Function	GO:0005267	potassium channel activity	Kcnk5	IDA		Mouse	MGI:MGI:5295108|PMID:21976511
Molecular Function	GO:0005267	potassium channel activity	kcnk5a	IDA		Zfish	PMID:24081451
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:O14798	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P18859	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P29033	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P29972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:P48230	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q8N138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q8N2U9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q969K7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q96HP8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q9Y2E5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNK5	IPI	UniProtKB:Q9Y6G1	Human	PMID:32296183
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnk5	IDA		Mouse	PMID:20351106
Biological Process	GO:0033333	fin development	kcnk5b	IMP	ZFIN:ZDB-GENO-150923-2	Zfish	PMID:24453984
Biological Process	GO:0033333	fin development	kcnk5b	IMP	ZFIN:ZDB-GENO-080206-1	Zfish	PMID:24453984
Biological Process	GO:0033334	fin morphogenesis	kcnk5b	IMP	ZFIN:ZDB-GENO-080206-1	Zfish	PMID:24173565
Biological Process	GO:0097623	potassium ion export across plasma membrane	Kcnk5	IDA		Mouse	MGI:MGI:5295108|PMID:21976511
Biological Process	GO:1990573	potassium ion import across plasma membrane	Kcnk5	IDA		Mouse	PMID:20351106
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnk5a	IDA		Zfish	PMID:24081451|ZFIN:ZDB-PUB-131105-3
Biological Process	GO:0006813	potassium ion transport	KCNK5	IDA		Human	PMID:9812978
Biological Process	GO:0042391	regulation of membrane potential	kcnk5b	IDA		Zfish	PMID:24453984
Biological Process	GO:0060075	regulation of resting membrane potential	Kcnk5	IDA		Mouse	MGI:MGI:5295108|PMID:21976511

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern