Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNK4
  • Mouse genes Kcnk4
  • Rat genes Catsperz,Kcnk4
  • Zfish genes kcnk4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnk4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098782	mechanosensitived potassium channel activity	KCNK4	IDA		Human	PMID:22282805
Molecular Function	GO:0098782	mechanosensitived potassium channel activity	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Molecular Function	GO:0005267	potassium channel activity	KCNK4	IDA		Human	PMID:22282805
Molecular Function	GO:0005267	potassium channel activity	Kcnk4	IDA		Rat	PMID:11374070|RGD:633146
Molecular Function	GO:0005267	potassium channel activity	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Molecular Function	GO:0097604	temperature-gated cation channel activity	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Cellular Component	GO:0005886	plasma membrane	KCNK4	IMP		Human	PMID:22282805
Cellular Component	GO:0005886	plasma membrane	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Cellular Component	GO:0034705	potassium channel complex	KCNK4	IDA		Human	PMID:22282805
Biological Process	GO:0071469	cellular response to alkaline pH	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Biological Process	GO:0071398	cellular response to fatty acid	KCNK4	IDA		Human	PMID:22282805
Biological Process	GO:0071398	cellular response to fatty acid	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Biological Process	GO:0071260	cellular response to mechanical stimulus	KCNK4	IDA		Human	PMID:22282805
Biological Process	GO:0071502	cellular response to temperature stimulus	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Biological Process	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch	Kcnk4	IMP		Mouse	MGI:MGI:3846268|PMID:19279663
Biological Process	GO:0007613	memory	Kcnk4	IEP		Rat	PMID:14730890|RGD:9831144
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNK4	IDA		Human	PMID:22282805
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnk4	IDA		Rat	PMID:15677687|RGD:10047327
Biological Process	GO:0019233	sensory perception of pain	Kcnk4	IMP		Mouse	MGI:MGI:3846268|PMID:19279663
Biological Process	GO:0050951	sensory perception of temperature stimulus	Kcnk4	IMP		Mouse	MGI:MGI:3846268|PMID:19279663

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern