Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNK18
  • Mouse genes Kcnk18
  • Rat genes Kcnk18
  • Zfish genes kcnk18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnk18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnk18	IDA		Mouse	MGI:MGI:4839430|PMID:20006580
Molecular Function	GO:0015269	calcium-activated potassium channel activity	Kcnk18	IDA		Mouse	PMID:14981085
Molecular Function	GO:0015271	outward rectifier potassium channel activity	KCNK18	IDA		Human	PMID:12754259
Molecular Function	GO:0015271	outward rectifier potassium channel activity	kcnk18	IDA		Zfish	PMID:24311292
Molecular Function	GO:0005515	protein binding	Kcnk18	IPI	UniProtKB:Q04917	Mouse	MGI:MGI:3801237|PMID:18397886
Cellular Component	GO:0005886	plasma membrane	KCNK18	IDA		Human	PMID:20006580
Cellular Component	GO:0005886	plasma membrane	Kcnk18	IDA		Mouse	MGI:MGI:4839430|PMID:20006580
Biological Process	GO:0071467	cellular response to pH	KCNK18	IDA		Human	PMID:12754259
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCNK18	IDA		Human	PMID:12754259
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnk18	IDA		Zfish	PMID:24311292|ZFIN:ZDB-PUB-140127-18
Biological Process	GO:0006813	potassium ion transport	KCNK18	IDA		Human	PMID:20006580
Biological Process	GO:0006813	potassium ion transport	Kcnk18	IDA		Mouse	MGI:MGI:4839430|PMID:20006580
Biological Process	GO:0006813	potassium ion transport	Kcnk18	IDA		Mouse	PMID:14981085
Biological Process	GO:0030322	stabilization of membrane potential	kcnk18	IDA		Zfish	PMID:24311292

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern