Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNJ6
  • Mouse genes Kcnj6
  • Rat genes Kcnj6
  • Zfish genes kcnj6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015467	G-protein activated inward rectifier potassium channel activity	Kcnj6	IDA		Mouse	PMID:7926018
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Kcnj6	IDA		Rat	PMID:15731196|RGD:2316504
Molecular Function	GO:0005267	potassium channel activity	Kcnj6	IDA		Mouse	PMID:20393461
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P14416-1	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P48544	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P48549	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q92806	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:A2A2V5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O00767	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O14798	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O15155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O60725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O75063	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P02808	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P05090	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P11215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P29400-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P30301	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P30519	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P54315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:P56851	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q14162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q53FV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q53HI1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q6UX40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q6UX98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q7L5N7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q8N912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q969E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q969S6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q96HA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9BQG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9BT09	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9BTX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9BWH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9BZW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9NZG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9UKR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9Y342	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9Y3D6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9Y548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9Y5Y5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ6	IPI	UniProtKB:Q9Y5Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kcnj6	IPI	UniProtKB:Q8K4V4	Rat	PMID:17828261|RGD:8554502
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnj6	IDA		Mouse	PMID:10956667
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnj6	IMP		Mouse	PMID:10956667
Cellular Component	GO:0030424	axon	Kcnj6	IDA		Rat	PMID:15305864|RGD:2316505
Cellular Component	GO:0009986	cell surface	Kcnj6	IDA		Rat	PMID:19118198|RGD:2316501
Cellular Component	GO:0005737	cytoplasm	Kcnj6	IDA		Rat	PMID:15305864|RGD:2316505
Cellular Component	GO:0030425	dendrite	Kcnj6	IDA		Rat	PMID:19118198|RGD:2316501
Cellular Component	GO:0005794	Golgi apparatus	KCNJ6	HDA		Human	PMID:16780588
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnj6	IDA		Rat	PMID:15305864|RGD:2316505
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Kcnj6	IDA		Mouse	PMID:19558451
Cellular Component	GO:0005886	plasma membrane	KCNJ6	HDA		Human	PMID:16780588
Cellular Component	GO:0042734	presynaptic membrane	Kcnj6	IDA		Mouse	PMID:19558451
Biological Process	GO:0071315	cellular response to morphine	Kcnj6	IEP		Rat	PMID:18178009|RGD:6483056
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Kcnj6	IDA		Mouse	MGI:MGI:7316516|PMID:10956667
Biological Process	GO:0099505	regulation of presynaptic membrane potential	Kcnj6	IDA		Mouse	MGI:MGI:7316516|PMID:10956667
Biological Process	GO:0051602	response to electrical stimulus	Kcnj6	IEP		Rat	PMID:10215164|RGD:2316513
Biological Process	GO:0042403	thyroid hormone metabolic process	Kcnj6	IMP	MGI:MGI:1856525	Mouse	MGI:MGI:85368

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern