Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNJ3
  • Mouse genes Kcnj3
  • Rat genes Kcnj3
  • Zfish genes kcnj3a,kcnj3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ3	IDA		Human	PMID:12297500
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ3	IDA		Human	PMID:20560207
Molecular Function	GO:0005515	protein binding	KCNJ3	IPI	UniProtKB:P14416-1	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ3	IPI	UniProtKB:P21917	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ3	IPI	UniProtKB:P48051	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ3	IPI	UniProtKB:P48544	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ3	IPI	UniProtKB:Q92806	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	Kcnj3	IPI	UniProtKB:P00517	Rat	PMID:19765080|RGD:8553590
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnj3	IDA		Rat	PMID:7576657|RGD:155230811
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnj3	IMP		Rat	PMID:7576657|RGD:155230811
Cellular Component	GO:0009986	cell surface	Kcnj3	IDA		Rat	PMID:19118198|RGD:2316501
Cellular Component	GO:0009897	external side of plasma membrane	Kcnj3	IDA		Rat	PMID:11561006|RGD:1581474
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Kcnj3	IDA		Mouse	PMID:19558451
Cellular Component	GO:0042734	presynaptic membrane	Kcnj3	IDA		Mouse	PMID:19558451
Cellular Component	GO:0030315	T-tubule	Kcnj3	IDA		Rat	PMID:11561006|RGD:1581474
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNJ3	IDA		Human	PMID:20560207
Biological Process	GO:1990573	potassium ion import across plasma membrane	KCNJ3	IDA		Human	PMID:20560207
Biological Process	GO:0051602	response to electrical stimulus	Kcnj3	IEP		Rat	PMID:10215164|RGD:2316513

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern