Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNH3
  • Mouse genes Kcnh3
  • Rat genes Kcnh3
  • Zfish genes kcnh3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnh3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106151	CNBH domain intrinsic ligand binding	kcnh3	IDA		Zfish	PMID:29567795
Molecular Function	GO:0042802	identical protein binding	kcnh3	IPI	UniProtKB:A8WHX9	Zfish	PMID:22230959|ZFIN:ZDB-PUB-120111-38
Molecular Function	GO:0005267	potassium channel activity	kcnh3	IDA		Zfish	PMID:24632450
Molecular Function	GO:0015079	potassium ion transmembrane transporter activity	kcnh3	IDA		Zfish	PMID:28443815
Molecular Function	GO:0005515	protein binding	KCNH3	IPI	UniProtKB:P04578	Human	PMID:20638388
Molecular Function	GO:0005249	voltage-gated potassium channel activity	kcnh3	IDA		Zfish	PMID:22230959
Molecular Function	GO:0005249	voltage-gated potassium channel activity	kcnh3	IDA		Zfish	PMID:28443815
Cellular Component	GO:0005886	plasma membrane	kcnh3	IDA		Zfish	PMID:28443815
Biological Process	GO:1990573	potassium ion import across plasma membrane	kcnh3	IDA		Zfish	PMID:28443815
Biological Process	GO:0006813	potassium ion transport	kcnh3	IDA		Zfish	PMID:28443815

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern