Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnd3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCND3
- Mouse genes Kcnd3
- Rat genes Kcnd3
- Zfish genes kcnd3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	KCND3	IDA		Human	PMID:21349352
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	KCND3	IDA		Human	PMID:21493962
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	Kcnd3	IDA		Rat	PMID:26016905\|RGD:11056211
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	Kcnd3	IMP		Rat	PMID:12150935\|RGD:1581443
Molecular Function	GO:0005216	monoatomic ion channel activity	Kcnd3	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005267	potassium channel activity	Kcnd3	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005515	protein binding	KCND3	IPI	UniProtKB:Q9NZI2	Human	PMID:17187064
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	PR:P63143	Mouse	PMID:15662035
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	RGD:708413	Rat	PMID:10794667\|RGD:1581444
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	UniProtKB:Q9NZI2	Rat	PMID:17057713\|RGD:13432266
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	RGD:3631	Rat	PMID:18565539\|RGD:6484256
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	RGD:70886	Rat	PMID:20849929\|RGD:7205509
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	RGD:70888	Rat	PMID:21147063\|RGD:7207197
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	UniProtKB:Q8N608	Rat	PMID:27198182\|RGD:13441205
Molecular Function	GO:0005515	protein binding	Kcnd3	IPI	UniProtKB:Q9VMB4	Rat	PMID:27198182\|RGD:13441205
Molecular Function	GO:0044325	transmembrane transporter binding	KCND3	IPI	UniProtKB:Q9NS61	Human	PMID:21493962
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd3	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd3	IMP		Rat	PMID:12150935\|RGD:1581443
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd3	IDA		Rat	PMID:12967630\|RGD:7207200
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd3	IDA		Rat	PMID:27198182\|RGD:13441205
Molecular Function	GO:0005249	voltage-gated potassium channel activity	kcnd3	IDA		Zfish	PMID:18261223
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	KCND3	IMP		Human	PMID:21349352
Cellular Component	GO:0005901	caveola	Kcnd3	IDA		Rat	PMID:20224290\|RGD:6902941
Cellular Component	GO:0030425	dendrite	Kcnd3	IDA		Rat	PMID:20849929\|RGD:7205509
Cellular Component	GO:0098982	GABA-ergic synapse	Kcnd3	IDA		Mouse	PMID:17122053
Cellular Component	GO:0016020	membrane	Kcnd3	IDA		Mouse	PMID:18603586
Cellular Component	GO:0043005	neuron projection	Kcnd3	IDA		Rat	PMID:15738276\|RGD:1581435
Cellular Component	GO:0043025	neuronal cell body	Kcnd3	IDA		Rat	PMID:15738276\|RGD:1581435
Cellular Component	GO:0043025	neuronal cell body	Kcnd3	IDA		Rat	PMID:20849929\|RGD:7205509
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	Kcnd3	IDA		Rat	PMID:12967630\|RGD:7207200
Cellular Component	GO:0005886	plasma membrane	Kcnd3	IDA		Rat	PMID:10325948\|RGD:628469
Cellular Component	GO:0005886	plasma membrane	Kcnd3	IDA		Rat	PMID:12967630\|RGD:7207200
Cellular Component	GO:0099634	postsynaptic specialization membrane	Kcnd3	IDA		Mouse	PMID:17122053
Cellular Component	GO:0034705	potassium channel complex	Kcnd3	IDA		Rat	PMID:26016905\|RGD:11056211
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCND3	IDA		Human	PMID:21493962
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd3	IDA		Rat	PMID:20224290\|RGD:6902941
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd3	IPI	UniProtKB:Q62897	Rat	PMID:27198182\|RGD:13441205
Biological Process	GO:0071773	cellular response to BMP stimulus	Kcnd3	IMP		Rat	PMID:23747723\|RGD:8847123
Biological Process	GO:0086009	membrane repolarization	KCND3	IDA		Human	PMID:21493962
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCND3	IDA		Human	PMID:21349352
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCND3	IDA		Human	PMID:21493962
Biological Process	GO:0097623	potassium ion export across plasma membrane	Kcnd3	IDA		Rat	PMID:26016905\|RGD:11056211
Biological Process	GO:1990573	potassium ion import across plasma membrane	Kcnd3	IDA		Rat	PMID:27198182\|RGD:13441205
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnd3	IDA		Zfish	PMID:18261223\|ZFIN:ZDB-PUB-080227-14
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	KCND3	IMP		Human	PMID:21349352
Biological Process	GO:0099625	ventricular cardiac muscle cell membrane repolarization	KCND3	IMP		Human	PMID:21349352

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.