Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNA3
  • Mouse genes Kcna3
  • Rat genes Kcna3
  • Zfish genes kcna3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcna3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcna3	IMP		Rat	PMID:14602579|RGD:1300201
Molecular Function	GO:0015271	outward rectifier potassium channel activity	Kcna3	IMP		Rat	PMID:14602579|RGD:1300201
Molecular Function	GO:0005515	protein binding	KCNA3	IPI	UniProtKB:Q07812	Human	PMID:18818304
Molecular Function	GO:0005515	protein binding	KCNA3	IPI	UniProtKB:Q9UPQ8	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	KCNA3	IPI	UniProtKB:Q09470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNA3	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kcna3	IPI	UniProtKB:P78352	Rat	PMID:7477295|RGD:8554588
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcna3	IMP		Rat	PMID:2555158|RGD:69870
Cellular Component	GO:0030424	axon	Kcna3	IDA		Mouse	MGI:MGI:4947004|PMID:21233214
Cellular Component	GO:0044305	calyx of Held	Kcna3	IDA		Rat	PMID:14614103|RGD:13702408
Cellular Component	GO:0098978	glutamatergic synapse	Kcna3	IDA		Rat	PMID:14614103|RGD:13702408
Cellular Component	GO:0045121	membrane raft	Kcna3	IDA		Rat	PMID:18218624|RGD:8554598
Cellular Component	GO:0005886	plasma membrane	Kcna3	IDA		Rat	PMID:18218624|RGD:8554598
Cellular Component	GO:0005886	plasma membrane	Kcna3	IMP		Rat	PMID:2555158|RGD:69870
Cellular Component	GO:0045211	postsynaptic membrane	Kcna3	IDA		Rat	PMID:14614103|RGD:13702408
Cellular Component	GO:0042734	presynaptic membrane	Kcna3	IDA		Rat	PMID:14614103|RGD:13702408
Biological Process	GO:0022038	corpus callosum development	Kcna3	IEP		Rat	PMID:22473424|RGD:10411906
Biological Process	GO:0021554	optic nerve development	Kcna3	IEP		Rat	PMID:22473424|RGD:10411906
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcna3	IMP		Rat	PMID:2555158|RGD:69870

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern