Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes JPH2
  • Mouse genes Jph2
  • Rat genes Jph2
  • Zfish genes jph2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Jph2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	Jph2	IDA		Mouse	MGI:MGI:6270069|PMID:30409805
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Jph2	IDA		Mouse	MGI:MGI:6270069|PMID:30409805
Molecular Function	GO:0070300	phosphatidic acid binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0001786	phosphatidylserine binding	JPH2	IDA		Human	PMID:24001019
Molecular Function	GO:0005515	protein binding	JPH2	IPI	UniProtKB:Q13507	Human	PMID:20095964
Molecular Function	GO:0005515	protein binding	Jph2	IPI	UniProtKB:G1U2U3	Mouse	MGI:MGI:5619746|PMID:19277847
Molecular Function	GO:0005515	protein binding	Jph2	IPI	PR:P51637	Mouse	PMID:15541368
Cellular Component	GO:0030314	junctional membrane complex	Jph2	IMP		Mouse	MGI:MGI:1861885|PMID:10949023
Cellular Component	GO:0016020	membrane	Jph2	IDA		Mouse	PMID:15541368
Cellular Component	GO:0005634	nucleus	Jph2	IDA		Mouse	MGI:MGI:6270069|PMID:30409805
Cellular Component	GO:0016529	sarcoplasmic reticulum	Jph2	IDA		Mouse	PMID:10949023
Cellular Component	GO:0030018	Z disc	Jph2	IDA		Mouse	PMID:10949023
Biological Process	GO:0055074	calcium ion homeostasis	JPH2	IDA		Human	PMID:20095964
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Jph2	IDA		Mouse	MGI:MGI:6270069|PMID:30409805
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Jph2	IDA		Mouse	MGI:MGI:6270069|PMID:30409805
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Jph2	IMP	MGI:MGI:1891502	Mouse	PMID:10949023
Biological Process	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	JPH2	IDA		Human	PMID:20095964
Biological Process	GO:0055024	regulation of cardiac muscle tissue development	Jph2	IMP		Mouse	MGI:MGI:1861885|PMID:10949023

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern