Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITPK1
  • Mouse genes Itpk1
  • Rat genes Itpk1
  • Zfish genes itpk1a,itpk1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itpk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047325	inositol tetrakisphosphate 1-kinase activity	ITPK1	EXP		Human	PMID:8662638
Molecular Function	GO:0000825	inositol tetrakisphosphate 6-kinase activity	ITPK1	IMP		Human	PMID:29883610
Molecular Function	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity	ITPK1	EXP		Human	PMID:11042108
Molecular Function	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity	ITPK1	EXP		Human	PMID:11042108
Cellular Component	GO:0016324	apical plasma membrane	Itpk1	IDA		Mouse	PMID:16537650
Biological Process	GO:0070266	necroptotic process	ITPK1	IMP		Human	PMID:29883610
Biological Process	GO:0021915	neural tube development	Itpk1	IMP	MGI:MGI:3587933	Mouse	PMID:19482943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern