Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ISX
  • Mouse genes Isx
  • Rat genes Isx
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Isx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Isx	IMP	MGI:MGI:3703167	Mouse	PMID:25701869
Molecular Function	GO:0005515	protein binding	ISX	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISX	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISX	IPI	UniProtKB:Q01974	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISX	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISX	IPI	UniProtKB:Q5T6F2	Human	PMID:32296183
Molecular Function	GO:0043565	sequence-specific DNA binding	Isx	IDA		Mouse	PMID:25701869
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISX	IDA		Human	PMID:28473536
Biological Process	GO:1904479	negative regulation of intestinal absorption	Isx	IMP	MGI:MGI:3703167	Mouse	PMID:25701869
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Isx	IMP	MGI:MGI:3775943	Mouse	PMID:18093975
Biological Process	GO:1901738	regulation of vitamin A metabolic process	Isx	IMP	MGI:MGI:3775943	Mouse	PMID:18093975

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern