Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ISLR2
  • Mouse genes Islr2
  • Rat genes Islr2
  • Zfish genes islr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Islr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:Q16617	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:Q86VI4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ISLR2	IPI	UniProtKB:Q96G30	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Islr2	IPI	UniProtKB:Q3UFB7	Mouse	MGI:MGI:4411944|PMID:19755105
Molecular Function	GO:0005515	protein binding	islr2	IPI	UniProtKB:A4JYH4	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	islr2	IPI	UniProtKB:A8BB27	Zfish	PMID:19765300
Cellular Component	GO:0009986	cell surface	Islr2	IDA		Mouse	MGI:MGI:4411944|PMID:19755105
Biological Process	GO:0045773	positive regulation of axon extension	Islr2	IMP		Mouse	MGI:MGI:4411944|PMID:19755105
Biological Process	GO:0031290	retinal ganglion cell axon guidance	islr2	IMP	ZFIN:ZDB-GENO-180705-1	Zfish	PMID:26492970

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern