Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IQSEC3
  • Mouse genes Iqsec3
  • Rat genes Iqsec3
  • Zfish genes iqsec3a,iqsec3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Iqsec3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Iqsec3	IPI	UniProtKB:Q8BUV3	Mouse	MGI:MGI:5800345|PMID:27609886
Molecular Function	GO:0005515	protein binding	Iqsec3	IPI	UniProtKB:Q9WVQ1	Mouse	MGI:MGI:4946863|PMID:21198641
Cellular Component	GO:0005829	cytosol	IQSEC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098982	GABA-ergic synapse	Iqsec3	IDA		Mouse	PMID:21198641
Cellular Component	GO:0098982	GABA-ergic synapse	Iqsec3	IDA		Rat	PMID:27002143|RGD:11564746
Cellular Component	GO:0098982	GABA-ergic synapse	Iqsec3	IMP		Rat	PMID:27002143|RGD:11564746
Cellular Component	GO:0098690	glycinergic synapse	Iqsec3	IDA		Mouse	PMID:21198641
Cellular Component	GO:0060077	inhibitory synapse	Iqsec3	IDA		Mouse	MGI:MGI:4946863|PMID:21198641
Cellular Component	GO:0005654	nucleoplasm	IQSEC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Iqsec3	IDA		Mouse	MGI:MGI:5800345|PMID:27609886
Cellular Component	GO:0045211	postsynaptic membrane	Iqsec3	IDA		Mouse	MGI:MGI:4946863|PMID:21198641
Cellular Component	GO:0099629	postsynaptic specialization of symmetric synapse	Iqsec3	IDA		Mouse	PMID:21198641
Biological Process	GO:0090630	activation of GTPase activity	Iqsec3	IDA		Rat	PMID:21198641|RGD:8554231
Biological Process	GO:0099173	postsynapse organization	Iqsec3	IDA		Rat	PMID:27002143|RGD:11564746
Biological Process	GO:0099173	postsynapse organization	Iqsec3	IMP		Rat	PMID:27002143|RGD:11564746
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	Iqsec3	IDA		Rat	PMID:21198641|RGD:8554231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern