Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IQCG
  • Mouse genes Iqcg
  • Rat genes Iqcg
  • Zfish genes iqcg
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Iqcg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	IQCG	IDA		Human	PMID:24787902
Molecular Function	GO:0005516	calmodulin binding	Iqcg	IDA		Mouse	MGI:MGI:5608638|PMID:24849454
Molecular Function	GO:0030544	Hsp70 protein binding	IQCG	IPI	UniProtKB:P11142	Human	PMID:24787902
Cellular Component	GO:0015629	actin cytoskeleton	IQCG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	IQCG	IDA		Human	PMID:24787902
Cellular Component	GO:0005737	cytoplasm	Iqcg	IDA		Mouse	MGI:MGI:5608638|PMID:24849454
Cellular Component	GO:0005829	cytosol	IQCG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Iqcg	IDA		Mouse	PMID:27914912
Cellular Component	GO:0070062	extracellular exosome	IQCG	HDA		Human	PMID:19056867
Cellular Component	GO:0002177	manchette	Iqcg	IDA		Mouse	MGI:MGI:5608638|PMID:24849454
Cellular Component	GO:0031514	motile cilium	Iqcg	IDA		Mouse	MGI:MGI:5608638|PMID:24849454
Cellular Component	GO:0031514	motile cilium	iqcg	IDA		Zfish	PMID:25139857
Cellular Component	GO:0036126	sperm flagellum	Iqcg	IDA		Mouse	MGI:MGI:5608638|PMID:24849454
Biological Process	GO:0060216	definitive hemopoiesis	iqcg	IMP	ZFIN:ZDB-MRPHLNO-160211-7	Zfish	PMID:24787902
Biological Process	GO:0060216	definitive hemopoiesis	iqcg	IMP	ZFIN:ZDB-MRPHLNO-160211-6	Zfish	PMID:24787902
Biological Process	GO:0060216	definitive hemopoiesis	iqcg	IGI	ZFIN:ZDB-MRPHLNO-121213-3,ZFIN:ZDB-MRPHLNO-160211-6	Zfish	PMID:24787902
Biological Process	GO:0007288	sperm axoneme assembly	Iqcg	IMP		Mouse	MGI:MGI:5608638|PMID:24849454
Biological Process	GO:0007286	spermatid development	Iqcg	IMP		Mouse	MGI:MGI:5608638|PMID:24849454
Biological Process	GO:0007286	spermatid development	Iqcg	IMP	MGI:MGI:3050608	Mouse	PMID:24362311

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern