Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INTS3
  • Mouse genes Ints3
  • Rat genes Ints3
  • Zfish genes ints3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ints3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:P24928	Human	PMID:16239144
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:O60934	Human	PMID:19683501
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:Q96AH0	Human	PMID:19683501
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:Q9BQ15	Human	PMID:19683501
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:Q9NRY2	Human	PMID:19683501
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:O43829	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INTS3	IPI	UniProtKB:Q9BQ15	Human	PMID:28506294
Cellular Component	GO:0005737	cytoplasm	INTS3	IDA		Human	PMID:23904267
Cellular Component	GO:0032039	integrator complex	INTS3	IDA		Human	PMID:16239144
Cellular Component	GO:0005634	nucleus	INTS3	IDA		Human	PMID:19683501
Cellular Component	GO:0005634	nucleus	INTS3	IDA		Human	PMID:23904267
Cellular Component	GO:0035861	site of double-strand break	INTS3	IDA		Human	PMID:19683501
Cellular Component	GO:0070876	SOSS complex	INTS3	IPI		Human	PMID:19683501
Cellular Component	GO:0070876	SOSS complex	INTS3	IPI		Human	PMID:24630995
Cellular Component	GO:0070876	SOSS complex	INTS3	IDA		Human	PMID:18449195
Cellular Component	GO:0070876	SOSS complex	INTS3	IDA		Human	PMID:19683501
Biological Process	GO:0006974	DNA damage response	INTS3	IMP		Human	PMID:19683501
Biological Process	GO:0006281	DNA repair	INTS3	IMP		Human	PMID:19605351
Biological Process	GO:0006281	DNA repair	INTS3	IMP		Human	PMID:19683501
Biological Process	GO:0000724	double-strand break repair via homologous recombination	INTS3	IDA		Human	PMID:19683501
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	INTS3	IDA		Human	PMID:19683501
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	INTS3	IMP		Human	PMID:19683501
Biological Process	GO:0010212	response to ionizing radiation	INTS3	IMP		Human	PMID:19605351
Biological Process	GO:0010212	response to ionizing radiation	INTS3	IMP		Human	PMID:19683501
Biological Process	GO:0016180	snRNA processing	INTS3	IDA		Human	PMID:16239144

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern