Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IMPACT
  • Mouse genes Impact
  • Rat genes Impact
  • Zfish genes impact
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Impact

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Impact	IDA		Mouse	MGI:MGI:5700292|PMID:22404850
Molecular Function	GO:0005515	protein binding	IMPACT	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IMPACT	IPI	UniProtKB:P36955	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Impact	IPI	UniProtKB:P04650|UniProtKB:P33892	Mouse	MGI:MGI:5700292|PMID:22404850
Molecular Function	GO:0005515	protein binding	Impact	IPI	PR:E9PVA8	Mouse	PMID:15937339
Molecular Function	GO:0043022	ribosome binding	Impact	IDA		Mouse	MGI:MGI:5700292|PMID:22404850
Cellular Component	GO:0005844	polysome	Impact	IDA		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0071468	cellular response to acidic pH	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0034198	cellular response to amino acid starvation	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0042149	cellular response to glucose starvation	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:1990253	cellular response to leucine starvation	Impact	IDA		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0071494	cellular response to UV-C	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0140469	GCN2-mediated signaling	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0060548	negative regulation of cell death	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Impact	IDA		Mouse	PMID:15937339
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	Impact	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:1990138	neuron projection extension	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0045666	positive regulation of neuron differentiation	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0071264	positive regulation of translational initiation in response to starvation	Impact	IMP		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0006446	regulation of translational initiation	Impact	IDA		Mouse	PMID:15937339

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern