Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL5RA
  • Mouse genes Il5ra
  • Rat genes Il5ra
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il5ra

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004914	interleukin-5 receptor activity	IL5RA	IDA		Human	PMID:22528658
Molecular Function	GO:0005515	protein binding	IL5RA	IPI	UniProtKB:O00560	Human	PMID:12842047
Molecular Function	GO:0005515	protein binding	IL5RA	IPI	UniProtKB:P05113	Human	PMID:1495999
Molecular Function	GO:0005515	protein binding	IL5RA	IPI	UniProtKB:P32927	Human	PMID:1495999
Molecular Function	GO:0005515	protein binding	IL5RA	IPI	UniProtKB:O60674	Human	PMID:9516124
Molecular Function	GO:0005515	protein binding	IL5RA	IPI	UniProtKB:P32927	Human	PMID:9516124
Cellular Component	GO:0005886	plasma membrane	IL5RA	IDA		Human	PMID:1495999
Biological Process	GO:0071310	cellular response to organic substance	Il5ra	IMP	MGI:MGI:2180501	Mouse	PMID:10848907
Biological Process	GO:0002437	inflammatory response to antigenic stimulus	Il5ra	IMP	MGI:MGI:2180501	Mouse	PMID:10848907
Biological Process	GO:0038043	interleukin-5-mediated signaling pathway	IL5RA	IDA		Human	PMID:22528658
Biological Process	GO:0032674	regulation of interleukin-5 production	Il5ra	IMP	MGI:MGI:2180501	Mouse	PMID:10848907

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern