Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL17RA
  • Mouse genes Il17ra
  • Rat genes Il17ra
  • Zfish genes il17ra1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il17ra

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030368	interleukin-17 receptor activity	IL17RA	IDA		Human	PMID:27184415
Molecular Function	GO:0030368	interleukin-17 receptor activity	IL17RA	IDA		Human	PMID:33723527
Molecular Function	GO:0030368	interleukin-17 receptor activity	Il17ra	IDA		Mouse	MGI:MGI:6694386|PMID:33723527
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:Q8NFR9	Human	PMID:21993848
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:Q16552	Human	PMID:23695682
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:O43734	Human	PMID:24120361
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:Q16552	Human	PMID:28827714
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:Q96PD4	Human	PMID:28827714
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:P0DTC8	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:P0DTC8	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	IL17RA	IPI	UniProtKB:P0DTC8	Human	PMID:33723527
Molecular Function	GO:0005515	protein binding	Il17ra	IPI	UniProtKB:P0DTC8|UniProtKB:Q8N7N6	Mouse	MGI:MGI:6694386|PMID:33723527
Molecular Function	GO:0005515	protein binding	Il17ra	IPI	UniProtKB:P70196	Mouse	PMID:19825828
Molecular Function	GO:0005515	protein binding	Il17ra	IPI	UniProtKB:Q01705	Mouse	PMID:28561022
Molecular Function	GO:0005102	signaling receptor binding	Il17ra	IPI	UniProtKB:Q8K4C2	Mouse	MGI:MGI:4462077|PMID:20554964
Cellular Component	GO:0005886	plasma membrane	Il17ra	IDA		Mouse	PMID:17911633
Biological Process	GO:0071345	cellular response to cytokine stimulus	Il17ra	IDA		Rat	PMID:21659501|RGD:5144218
Biological Process	GO:0050832	defense response to fungus	Il17ra	IMP		Mouse	MGI:MGI:4462077|PMID:20554964
Biological Process	GO:0072537	fibroblast activation	IL17RA	IDA		Human	PMID:21145111
Biological Process	GO:0071621	granulocyte chemotaxis	Il17ra	IMP		Mouse	MGI:MGI:4462077|PMID:20554964
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IL17RA	IMP		Human	PMID:21350122
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IL17RA	IDA		Human	PMID:33723527
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Il17ra	IDA		Mouse	MGI:MGI:6694386|PMID:33723527
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Il17ra	IDA		Mouse	PMID:28561022
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Il17ra	IDA		Mouse	PMID:19825828
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	IL17RA	IDA		Human	PMID:9367539
Biological Process	GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	IL17RA	IMP		Human	PMID:21350122
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IL17RA	IDA		Human	PMID:33723527
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Il17ra	IDA		Mouse	MGI:MGI:6694386|PMID:33723527
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Il17ra	IGI	MGI:MGI:2676631	Mouse	PMID:16785495
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Il17ra	IGI	MGI:MGI:107364	Mouse	PMID:16785495
Biological Process	GO:0050729	positive regulation of inflammatory response	IL17RA	IDA		Human	PMID:33723527
Biological Process	GO:0050729	positive regulation of inflammatory response	Il17ra	IDA		Mouse	MGI:MGI:6694386|PMID:33723527
Biological Process	GO:0050729	positive regulation of inflammatory response	Il17ra	IMP	MGI:MGI:2450882	Mouse	PMID:18768888
Biological Process	GO:0032736	positive regulation of interleukin-13 production	Il17ra	IMP	MGI:MGI:2450882	Mouse	PMID:18768888
Biological Process	GO:0032747	positive regulation of interleukin-23 production	IL17RA	IDA		Human	PMID:21145111
Biological Process	GO:0032754	positive regulation of interleukin-5 production	Il17ra	IMP	MGI:MGI:2450882	Mouse	PMID:18768888
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IL17RA	IMP		Human	PMID:21350122
Biological Process	GO:0030163	protein catabolic process	Il17ra	IDA		Mouse	PMID:28561022
Biological Process	GO:0009615	response to virus	IL17RA	IDA		Human	PMID:33723527
Biological Process	GO:0009615	response to virus	Il17ra	IDA		Mouse	MGI:MGI:6694386|PMID:33723527
Biological Process	GO:0072538	T-helper 17 type immune response	Il17ra	IDA		Mouse	PMID:28561022

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern