Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IKZF5
  • Mouse genes Ikzf5
  • Rat genes Ikzf5
  • Zfish genes ikzf5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ikzf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	IKZF5	IMP		Human	PMID:31217188
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IKZF5	IDA		Human	PMID:10978333
Molecular Function	GO:0005515	protein binding	IKZF5	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0005515	protein binding	IKZF5	IPI	UniProtKB:Q9UKT9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF5	IPI	UniProtKB:Q9UKT9	Human	PMID:28514442
Molecular Function	GO:0019904	protein domain specific binding	IKZF5	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IKZF5	IDA		Human	PMID:10978333
Molecular Function	GO:0008270	zinc ion binding	IKZF5	IMP		Human	PMID:15491138
Cellular Component	GO:0005634	nucleus	IKZF5	IMP		Human	PMID:31217188
Cellular Component	GO:0032991	protein-containing complex	IKZF5	IMP		Human	PMID:15491138
Biological Process	GO:0071908	determination of intestine left/right asymmetry	ikzf5	IMP	ZFIN:ZDB-MRPHLNO-130809-3	Zfish	PMID:23499657
Biological Process	GO:0071908	determination of intestine left/right asymmetry	ikzf5	IMP	ZFIN:ZDB-MRPHLNO-140519-1	Zfish	PMID:23499657
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	ikzf5	IMP	ZFIN:ZDB-MRPHLNO-130809-3	Zfish	PMID:23499657
Biological Process	GO:0007368	determination of left/right symmetry	ikzf5	IMP	ZFIN:ZDB-MRPHLNO-130809-3	Zfish	PMID:23499657
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	ikzf5	IMP	ZFIN:ZDB-MRPHLNO-130809-3	Zfish	PMID:23499657
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IKZF5	IDA		Human	PMID:10978333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern