Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGFALS
  • Mouse genes Igfals
  • Rat genes Igfals
  • Zfish genes igfals
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igfals

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005520	insulin-like growth factor binding	Igfals	IDA		Rat	PMID:12446576|RGD:1299153
Molecular Function	GO:0005515	protein binding	Igfals	IPI	PR:P12815	Mouse	PMID:11591653
Cellular Component	GO:0070062	extracellular exosome	IGFALS	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	IGFALS	HDA		Human	PMID:23533145
Cellular Component	GO:0042567	insulin-like growth factor ternary complex	IGFALS	IDA		Human	PMID:9497324
Cellular Component	GO:0042567	insulin-like growth factor ternary complex	Igfals	IDA		Rat	PMID:12446576|RGD:1299153
Cellular Component	GO:0042567	insulin-like growth factor ternary complex	Igfals	IDA		Rat	PMID:9346943|RGD:1626111
Biological Process	GO:0007568	aging	Igfals	IEP		Rat	PMID:9751511|RGD:10402778
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Igfals	IEP		Rat	PMID:8070348|RGD:12911020
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Igfals	IEP		Rat	PMID:8070348|RGD:12911020
Biological Process	GO:0071378	cellular response to growth hormone stimulus	Igfals	IEP		Rat	PMID:9473516|RGD:12910942
Biological Process	GO:0071347	cellular response to interleukin-1	Igfals	IEP		Rat	PMID:9473516|RGD:12910942
Biological Process	GO:0031667	response to nutrient levels	Igfals	IEP		Rat	PMID:10444419|RGD:12910943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern