Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT46
  • Mouse genes Ift46
  • Rat genes Ift46
  • Zfish genes ift46
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift46

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Ift46	IPI	UniProtKB:Q8N136	Mouse	MGI:MGI:6393006|PMID:18852297
Molecular Function	GO:0005515	protein binding	Ift46	IPI	UniProtKB:Q8BS45	Mouse	MGI:MGI:5608603|PMID:25340710
Molecular Function	GO:0005515	protein binding	Ift46	IPI	PR:Q61371	Mouse	PMID:17312020
Molecular Function	GO:0005515	protein binding	Ift46	IPI	PR:Q8BXG3	Mouse	PMID:17312020
Cellular Component	GO:0005813	centrosome	Ift46	IDA		Mouse	PMID:19253336
Cellular Component	GO:0036064	ciliary basal body	ift46	IDA		Zfish	PMID:25722189
Cellular Component	GO:0005929	cilium	Ift46	IDA		Mouse	PMID:19253336
Cellular Component	GO:0005929	cilium	Ift46	IDA		Mouse	PMID:17720815
Cellular Component	GO:0005737	cytoplasm	IFT46	IDA		Human	GO_REF:0000054
Cellular Component	GO:0030992	intraciliary transport particle B	IFT46	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift46	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift46	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift46	IDA		Mouse	PMID:17312020
Cellular Component	GO:0030992	intraciliary transport particle B	Ift46	IDA		Mouse	PMID:19253336
Cellular Component	GO:0031514	motile cilium	Ift46	IDA		Mouse	PMID:17312020
Biological Process	GO:0060271	cilium assembly	Ift46	IMP		Mouse	PMID:21289087
Biological Process	GO:0060271	cilium assembly	ift46	IMP	ZFIN:ZDB-MRPHLNO-150618-1	Zfish	PMID:25722189
Biological Process	GO:0048264	determination of ventral identity	ift46	IMP	ZFIN:ZDB-MRPHLNO-080102-1	Zfish	PMID:17720815
Biological Process	GO:0048793	pronephros development	ift46	IMP	ZFIN:ZDB-MRPHLNO-150618-1	Zfish	PMID:25722189
Biological Process	GO:0060041	retina development in camera-type eye	ift46	IMP	ZFIN:ZDB-MRPHLNO-150618-1	Zfish	PMID:25722189
Biological Process	GO:0007224	smoothened signaling pathway	Ift46	IMP		Mouse	PMID:21289087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern