Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFNLR1
  • Mouse genes Ifnlr1
  • Rat genes Ifnlr1
  • Zfish genes crfb2,ifnlr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifnlr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004904	interferon receptor activity	crfb2	IGI	ZFIN:ZDB-GENE-071128-2,ZFIN:ZDB-MRPHLNO-070906-4	Zfish	PMID:19717522
Molecular Function	GO:0004904	interferon receptor activity	crfb2	IGI	ZFIN:ZDB-GENE-071128-1,ZFIN:ZDB-MRPHLNO-070906-4	Zfish	PMID:19717522
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:Q8IU54	Human	PMID:12469119
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:Q08334	Human	PMID:12483210
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:P09466	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:Q6PL45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFNLR1	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Cellular Component	GO:0032002	interleukin-28 receptor complex	IFNLR1	IDA		Human	PMID:12469119
Biological Process	GO:0051607	defense response to virus	Ifnlr1	IMP		Mouse	MGI:MGI:5009066|PMID:21518880
Biological Process	GO:0051607	defense response to virus	Ifnlr1	IGI	MGI:MGI:2156367	Mouse	PMID:18250457
Biological Process	GO:0051607	defense response to virus	Ifnlr1	IGI	MGI:MGI:1932389	Mouse	PMID:18250457
Biological Process	GO:0002385	mucosal immune response	Ifnlr1	IMP		Mouse	MGI:MGI:5009066|PMID:21518880
Biological Process	GO:0048884	neuromast development	ifnlr1	IMP	ZFIN:ZDB-MRPHLNO-180913-1	Zfish	PMID:29453195
Biological Process	GO:1901857	positive regulation of cellular respiration	IFNLR1	IMP		Human	PMID:25930096
Biological Process	GO:0050691	regulation of defense response to virus by host	IFNLR1	IDA		Human	PMID:12469119

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern