Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ICA1
  • Mouse genes Ica1
  • Rat genes Ica1
  • Zfish genes ica1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ica1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140090	membrane curvature sensor activity	ICA1	IDA		Human	PMID:29768204
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:O95983	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:P61019	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:Q7Z6N9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:Q8IWP9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:Q8WUD1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:Q8WYH8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:P61019	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ICA1	IPI	UniProtKB:Q8WUD1	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	Ica1	IPI	UniProtKB:Q62083	Mouse	MGI:MGI:5494331|PMID:23630453
Molecular Function	GO:0019904	protein domain specific binding	Ica1	IMP		Rat	PMID:18032668|RGD:2303404
Cellular Component	GO:0005829	cytosol	ICA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Ica1	IDA		Mouse	MGI:MGI:1926685|PMID:11029035
Cellular Component	GO:0030425	dendrite	Ica1	IDA		Rat	PMID:18032668|RGD:2303404
Cellular Component	GO:0000139	Golgi membrane	ICA1	IDA		Human	PMID:12682071
Cellular Component	GO:0000139	Golgi membrane	Ica1	IDA		Rat	PMID:12682071|RGD:724603
Cellular Component	GO:0005795	Golgi stack	Ica1	IDA		Rat	PMID:12682071|RGD:724603
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ICA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ica1	IDA		Rat	PMID:12682071|RGD:724603
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ica1	IDA		Rat	PMID:18032668|RGD:2303404
Cellular Component	GO:0030667	secretory granule membrane	ICA1	IDA		Human	PMID:12682071
Cellular Component	GO:0030672	synaptic vesicle membrane	Ica1	IDA		Mouse	MGI:MGI:1926685|PMID:11029035
Biological Process	GO:0043254	regulation of protein-containing complex assembly	Ica1	IMP		Rat	PMID:18032668|RGD:2303404

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern