Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSPH1
  • Mouse genes Hsph1
  • Rat genes Hsph1
  • Zfish genes hsph1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsph1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000774	adenyl-nucleotide exchange factor activity	HSPH1	IDA		Human	PMID:24318877
Molecular Function	GO:0043014	alpha-tubulin binding	Hsph1	IDA		Mouse	MGI:MGI:5009181|PMID:12749852
Molecular Function	GO:0005515	protein binding	HSPH1	IPI	UniProtKB:Q62392	Human	PMID:17024176
Molecular Function	GO:0005515	protein binding	HSPH1	IPI	UniProtKB:Q8WXB1	Human	PMID:23349634
Molecular Function	GO:0005515	protein binding	HSPH1	IPI	UniProtKB:P0DMV8	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	HSPH1	IPI	UniProtKB:P0DMV9	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	HSPH1	IPI	UniProtKB:Q96BE0	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	Hsph1	IPI	PR:P29752	Mouse	PMID:14644449
Cellular Component	GO:0005737	cytoplasm	HSPH1	IDA		Human	PMID:9931472
Cellular Component	GO:0005829	cytosol	HSPH1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	HSPH1	IDA		Human	PMID:21231916
Cellular Component	GO:0070062	extracellular exosome	HSPH1	HDA		Human	PMID:20458337
Cellular Component	GO:0005874	microtubule	Hsph1	IDA		Mouse	MGI:MGI:5009181|PMID:12749852
Cellular Component	GO:0005654	nucleoplasm	HSPH1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	HSPH1	IDA		Human	PMID:23349634
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	Hsph1	IDA		Mouse	PMID:14644449

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern