Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hspa9

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HSPA9
- Mouse genes Hspa9
- Rat genes Hspa9
- Zfish genes hspa9
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hspa9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Hspa9	IPI	UniProtKB:P53602	Mouse	MGI:MGI:3852312\|PMID:12646231
Molecular Function	GO:0017134	fibroblast growth factor binding	Hspa9	IPI	RGD:2605	Rat	PMID:10510314\|RGD:10402562
Molecular Function	GO:0017134	fibroblast growth factor binding	Hspa9	IPI	RGD:2605	Rat	PMID:15030183\|RGD:6784522
Molecular Function	GO:0031072	heat shock protein binding	Hspa9	IPI	RGD:1306527	Rat	PMID:15030183\|RGD:6784522
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q96EY1	Human	PMID:10411904
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q96EY1-1	Human	PMID:15520177
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q96EY1-2	Human	PMID:15520177
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P04637	Human	PMID:17184779
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P04637	Human	PMID:20153329
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q8WX92	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q8IWL3	Human	PMID:20668094
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:O15350	Human	PMID:22340593
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P04637	Human	PMID:22340593
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P04637	Human	PMID:22726440
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q86YL7	Human	PMID:23541579
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q9H1K1	Human	PMID:23940031
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q8IWL3	Human	PMID:24606901
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:A4D2J0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q16595\|UniProtKB:Q9H1K1\|UniProtKB:Q9UMS0\|UniProtKB:Q9Y697	Human	PMID:26702583
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P13693	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q8IWL3	Human	PMID:28380382
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q9HAV7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q9HAV7	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	HSPA9	IPI	UniProtKB:Q99650	Human	PMID:32807793
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	PR:Q99M87	Mouse	PMID:14993262
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	PR:P02340	Mouse	PMID:11900485
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	RGD:620218	Rat	PMID:16207717\|RGD:10059428
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	RGD:71058	Rat	PMID:16518874\|RGD:10054427
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	RGD:2268	Rat	PMID:19833151\|RGD:13792654
Molecular Function	GO:0005515	protein binding	Hspa9	IPI	RGD:3864	Rat	PMID:9538267\|RGD:70039
Molecular Function	GO:0051087	protein-folding chaperone binding	Hspa9	IPI	RGD:70947	Rat	PMID:9694873\|RGD:13461858
Molecular Function	GO:0003723	RNA binding	HSPA9	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	HSPA9	HDA		Human	PMID:22681889
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HSPA9	IPI	UniProtKB:O60260	Human	PMID:19725078
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HSPA9	IPI	UniProtKB:O60260	Human	PMID:21753002
Cellular Component	GO:0005737	cytoplasm	Hspa9	IDA		Rat	PMID:17109810\|RGD:10402564
Cellular Component	GO:0070062	extracellular exosome	HSPA9	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	HSPA9	HDA		Human	PMID:21423176
Cellular Component	GO:0140275	MIB complex	HSPA9	HDA		Human	PMID:26477565
Cellular Component	GO:0005759	mitochondrial matrix	Hspa9	IDA		Mouse	PMID:28376086
Cellular Component	GO:0005759	mitochondrial matrix	Hspa9	IDA		Mouse	PMID:11092755
Cellular Component	GO:0042645	mitochondrial nucleoid	HSPA9	IDA		Human	PMID:18063578
Cellular Component	GO:0005739	mitochondrion	HSPA9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	HSPA9	IDA		Human	PMID:26702583
Cellular Component	GO:0005739	mitochondrion	HSPA9	IDA		Human	PMID:7896880
Cellular Component	GO:0005739	mitochondrion	Hspa9	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Hspa9	IDA		Mouse	PMID:12931191
Cellular Component	GO:0005739	mitochondrion	Hspa9	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Hspa9	IDA		Mouse	PMID:14993262
Cellular Component	GO:0005739	mitochondrion	Hspa9	IDA		Rat	PMID:7811387\|RGD:13461859
Cellular Component	GO:0043209	myelin sheath	Hspa9	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0001401	SAM complex	HSPA9	HDA		Human	PMID:26477565
Biological Process	GO:0071347	cellular response to interleukin-1	Hspa9	IEP		Rat	PMID:15621568\|RGD:6784519
Biological Process	GO:0030218	erythrocyte differentiation	HSPA9	IMP		Human	PMID:21123823
Biological Process	GO:0031101	fin regeneration	hspa9	IMP	ZFIN:ZDB-GENO-091104-1	Zfish	PMID:18950614
Biological Process	GO:0030097	hemopoiesis	hspa9	IMP	ZFIN:ZDB-GENO-091104-1	Zfish	PMID:18950614
Biological Process	GO:0030097	hemopoiesis	hspa9	IMP	ZFIN:ZDB-MRPHLNO-050711-1	Zfish	PMID:15650063
Biological Process	GO:0030097	hemopoiesis	hspa9	IMP	ZFIN:ZDB-GENO-060524-1	Zfish	PMID:15650063
Biological Process	GO:0016226	iron-sulfur cluster assembly	HSPA9	IMP		Human	PMID:26702583
Biological Process	GO:0016226	iron-sulfur cluster assembly	Hspa9	IMP		Mouse	MGI:MGI:6094650\|PMID:26702583
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	HSPA9	IMP		Human	PMID:21123823
Biological Process	GO:1902037	negative regulation of hematopoietic stem cell differentiation	Hspa9	IMP		Mouse	MGI:MGI:5784980\|PMID:21123823
Biological Process	GO:1903707	negative regulation of hemopoiesis	Hspa9	IMP		Mouse	MGI:MGI:5784980\|PMID:21123823
Biological Process	GO:0046777	protein autophosphorylation	Hspa9	IDA		Rat	PMID:7811387\|RGD:13461859
Biological Process	GO:0006611	protein export from nucleus	Hspa9	IDA		Mouse	PMID:11900485
Biological Process	GO:0045646	regulation of erythrocyte differentiation	HSPA9	IMP		Human	PMID:26702583
Biological Process	GO:0051593	response to folic acid	Hspa9	IEP		Rat	PMID:16251605\|RGD:2306623
Biological Process	GO:0097068	response to thyroxine	Hspa9	IEP		Rat	PMID:21563808\|RGD:5147909
Biological Process	GO:0009636	response to toxic substance	Hspa9	IEP		Rat	PMID:7901206\|RGD:6784527

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.