Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSD17B2
  • Mouse genes Hsd17b2
  • Rat genes Hsd17b2
  • Zfish genes hsd17b2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd17b2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	HSD17B2	IDA		Human	PMID:17538076
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	HSD17B2	IDA		Human	PMID:8099587
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b2	IDA		Rat	PMID:8612487|RGD:728619
Molecular Function	GO:0047035	testosterone dehydrogenase (NAD+) activity	HSD17B2	IDA		Human	PMID:8099587
Molecular Function	GO:0047035	testosterone dehydrogenase (NAD+) activity	Hsd17b2	IDA		Rat	PMID:8612487|RGD:728619
Cellular Component	GO:0005789	endoplasmic reticulum membrane	HSD17B2	IDA		Human	PMID:10385431
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Hsd17b2	IDA		Rat	PMID:16940216|RGD:4891018
Biological Process	GO:0006702	androgen biosynthetic process	Hsd17b2	IDA		Rat	PMID:8612487|RGD:728619
Biological Process	GO:0008209	androgen metabolic process	HSD17B2	IDA		Human	PMID:11940569
Biological Process	GO:0060348	bone development	Hsd17b2	IEP		Rat	PMID:15012600|RGD:4891061
Biological Process	GO:0071248	cellular response to metal ion	Hsd17b2	IEP		Rat	PMID:18602937|RGD:4890967
Biological Process	GO:0006703	estrogen biosynthetic process	HSD17B2	IDA		Human	PMID:11940569
Biological Process	GO:0006703	estrogen biosynthetic process	Hsd17b2	IDA		Rat	PMID:8612487|RGD:728619
Biological Process	GO:0001701	in utero embryonic development	Hsd17b2	IMP	MGI:MGI:3773836	Mouse	PMID:18048640
Biological Process	GO:0001890	placenta development	Hsd17b2	IMP	MGI:MGI:3773836	Mouse	PMID:18048640
Biological Process	GO:0032526	response to retinoic acid	HSD17B2	IDA		Human	PMID:17538076

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern