Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSD17B12
  • Mouse genes Hsd17b12
  • Rat genes Hsd17b12
  • Zfish genes hsd17b12a,hsd17b12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd17b12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Hsd17b12	IDA		Mouse	PMID:18757743
Molecular Function	GO:0001968	fibronectin binding	Hsd17b12	IDA		Mouse	PMID:18757743
Molecular Function	GO:0008201	heparin binding	Hsd17b12	IDA		Mouse	PMID:18757743
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	HSD17B12	EXP		Human	PMID:12482854
Molecular Function	GO:0050062	long-chain-fatty-acyl-CoA reductase activity	HSD17B12	IDA		Human	PMID:25003994
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:A1L3X0	Human	PMID:20937905
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9BW60	Human	PMID:20937905
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9WMX2:PRO_0000037541	Human	PMID:24169621
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSD17B12	IPI	UniProtKB:P22607	Human	PMID:35384245
Cellular Component	GO:0031012	extracellular matrix	Hsd17b12	IDA		Mouse	PMID:18757743
Cellular Component	GO:0009923	fatty acid elongase complex	HSD17B12	IDA		Human	PMID:25003994
Biological Process	GO:0030198	extracellular matrix organization	Hsd17b12	IDA		Mouse	PMID:18757743
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Hsd17b12	IDA		Mouse	PMID:18757743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern