Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HPS5
  • Mouse genes Hps5
  • Rat genes Hps5
  • Zfish genes hps5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hps5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HPS5	IPI	UniProtKB:Q86YV9	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	HPS5	IPI	UniProtKB:A0A0H3NFP4	Human	PMID:31611645
Molecular Function	GO:0005515	protein binding	Hps5	IPI	PR:Q8BLY7	Mouse	PMID:12548288
Molecular Function	GO:0005515	protein binding	hps5	IPI	ZFIN:ZDB-GENE-061110-115	Zfish	PMID:23893484
Molecular Function	GO:0005515	protein binding	hps5	IPI	ZFIN:ZDB-GENE-100927-1	Zfish	PMID:23893484
Cellular Component	GO:0031084	BLOC-2 complex	HPS5	IPI		Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS5	IPI	UniProtKB:Q86YV9	Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS5	IPI	UniProtKB:Q969F9	Human	PMID:15030569
Cellular Component	GO:0005829	cytosol	HPS5	IDA		Human	GO_REF:0000052
Biological Process	GO:0007596	blood coagulation	Hps5	IMP	MGI:MGI:1856146	Mouse	PMID:6696991
Biological Process	GO:0048066	developmental pigmentation	hps5	IMP	ZFIN:ZDB-GENO-120228-47	Zfish	PMID:9007234
Biological Process	GO:0030903	notochord development	hps5	IMP	ZFIN:ZDB-GENO-120228-47	Zfish	PMID:9007234
Biological Process	GO:0006996	organelle organization	Hps5	IMP	MGI:MGI:1856144	Mouse	PMID:12548288
Biological Process	GO:0043473	pigmentation	Hps5	IMP	MGI:MGI:1856147	Mouse	PMID:2379821
Biological Process	GO:0043473	pigmentation	hps5	IMP	ZFIN:ZDB-GENO-131202-5	Zfish	PMID:23893484
Biological Process	GO:0043473	pigmentation	hps5	IMP	ZFIN:ZDB-MRPHLNO-131202-2	Zfish	PMID:23893484
Biological Process	GO:0048076	regulation of compound eye pigmentation	hps5	IMP	ZFIN:ZDB-GENO-131202-5	Zfish	PMID:23893484
Biological Process	GO:0048076	regulation of compound eye pigmentation	hps5	IMP	ZFIN:ZDB-MRPHLNO-131202-2	Zfish	PMID:23893484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern