Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOPX
  • Mouse genes Hopx
  • Rat genes Hopx
  • Zfish genes hopx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hopx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035033	histone deacetylase regulator activity	Hopx	IGI	MGI:MGI:1097691	Mouse	PMID:12975471
Molecular Function	GO:0005515	protein binding	HOPX	IPI	UniProtKB:Q99081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOPX	IPI	UniProtKB:P0DMV8	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HOPX	IPI	UniProtKB:P0DMV9	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HOPX	IPI	UniProtKB:P11142	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HOPX	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hopx	IPI	UniProtKB:P97471	Mouse	MGI:MGI:5917473|PMID:26113728
Molecular Function	GO:0005515	protein binding	Hopx	IPI	UniProtKB:P11831	Mouse	PMID:12297046
Molecular Function	GO:0005515	protein binding	Hopx	IPI	PR:P70288	Mouse	PMID:12975471
Cellular Component	GO:0005634	nucleus	HOPX	IDA		Human	PMID:17192267
Cellular Component	GO:0005634	nucleus	Hopx	IDA		Mouse	PMID:12297045
Cellular Component	GO:0005634	nucleus	Hopx	IDA		Mouse	PMID:16410412
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	HOPX	IDA		Human	PMID:10811660
Biological Process	GO:0007507	heart development	Hopx	IMP	MGI:MGI:2389233	Mouse	PMID:12297046
Biological Process	GO:0007507	heart development	Hopx	IMP	MGI:MGI:2389244	Mouse	PMID:12297045
Biological Process	GO:0007507	heart development	Hopx	IMP	MGI:MGI:2389236	Mouse	PMID:12297045
Biological Process	GO:0007507	heart development	hopx	IMP	ZFIN:ZDB-MRPHLNO-111024-3	Zfish	PMID:12297045
Biological Process	GO:0007507	heart development	hopx	IMP	ZFIN:ZDB-MRPHLNO-111024-2	Zfish	PMID:12297045
Biological Process	GO:0048286	lung alveolus development	Hopx	IMP	MGI:MGI:2389244	Mouse	PMID:16510470
Biological Process	GO:0045596	negative regulation of cell differentiation	HOPX	IDA		Human	PMID:17576768
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hopx	IGI	MGI:MGI:107516	Mouse	PMID:17409236
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hopx	IDA		Mouse	PMID:12297045
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hopx	IGI	MGI:MGI:108067	Mouse	PMID:17409236
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hopx	IGI	MGI:MGI:106658	Mouse	PMID:17409236
Biological Process	GO:1903598	positive regulation of gap junction assembly	Hopx	IMP		Mouse	MGI:MGI:3624209|PMID:15790958
Biological Process	GO:0043415	positive regulation of skeletal muscle tissue regeneration	Hopx	IMP	MGI:MGI:2389244	Mouse	PMID:17192267
Biological Process	GO:0051155	positive regulation of striated muscle cell differentiation	Hopx	IMP	MGI:MGI:2389244	Mouse	PMID:17192267
Biological Process	GO:0008016	regulation of heart contraction	Hopx	IMP	MGI:MGI:2389244	Mouse	PMID:15790958
Biological Process	GO:0043393	regulation of protein binding	Hopx	IDA		Mouse	PMID:20833366
Biological Process	GO:0001829	trophectodermal cell differentiation	HOPX	IDA		Human	PMID:17576768
Biological Process	GO:0001829	trophectodermal cell differentiation	Hopx	IMP	MGI:MGI:2389233	Mouse	PMID:17576768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern