Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HMX2
  • Mouse genes Hmx2
  • Rat genes Hmx2
  • Zfish genes hmx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hmx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HMX2	IDA		Human	PMID:28473536
Biological Process	GO:0007420	brain development	Hmx2	IGI	MGI:MGI:107160	Mouse	PMID:15363417
Biological Process	GO:0008283	cell population proliferation	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138
Biological Process	GO:0050673	epithelial cell proliferation	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138
Biological Process	GO:0042472	inner ear morphogenesis	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138
Biological Process	GO:0042472	inner ear morphogenesis	Hmx2	IGI	MGI:MGI:107160	Mouse	PMID:15363417
Biological Process	GO:0042472	inner ear morphogenesis	hmx2	IGI	ZFIN:ZDB-MRPHLNO-100602-1,ZFIN:ZDB-MRPHLNO-100602-2	Zfish	PMID:20043901
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	Hmx2	IMP		Mouse	PMID:23636947
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138
Biological Process	GO:0048916	posterior lateral line development	hmx2	IGI	ZFIN:ZDB-MRPHLNO-100602-1,ZFIN:ZDB-MRPHLNO-100602-2	Zfish	PMID:20043901
Biological Process	GO:0072089	stem cell proliferation	Hmx2	IMP	MGI:MGI:2154542	Mouse	PMID:11748138

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern