Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HJV
  • Mouse genes Hjv
  • Rat genes Hjv
  • Zfish genes hjv
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hjv

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036122	BMP binding	HJV	IPI	UniProtKB:P12643	Human	PMID:18335997
Molecular Function	GO:0036122	BMP binding	Hjv	IPI	UniProtKB:P12643|UniProtKB:P12644	Mouse	MGI:MGI:3625588|PMID:16604073
Molecular Function	GO:0036122	BMP binding	Hjv	IDA		Mouse	PMID:16604073
Molecular Function	GO:0098821	BMP receptor activity	HJV	IDA		Human	PMID:16604073
Molecular Function	GO:0015026	coreceptor activity	HJV	IDA		Human	PMID:16604073
Molecular Function	GO:0015026	coreceptor activity	Hjv	IGI	MGI:MGI:88177	Mouse	PMID:16604073
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:P12643	Human	PMID:18335997
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:Q92859	Human	PMID:18335997
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:Q8IU80-4	Human	PMID:18976966
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:Q8IU80	Human	PMID:19357398
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:Q8IU80-4	Human	PMID:19357398
Molecular Function	GO:0005515	protein binding	HJV	IPI	UniProtKB:Q30201	Human	PMID:22728873
Molecular Function	GO:0005102	signaling receptor binding	HJV	IPI	UniProtKB:P97798	Human	PMID:18326817
Molecular Function	GO:0005102	signaling receptor binding	HJV	IPI	UniProtKB:Q92859	Human	PMID:18335997
Molecular Function	GO:1990459	transferrin receptor binding	HJV	IPI	UniProtKB:Q9UP52	Human	PMID:22728873
Cellular Component	GO:0016323	basolateral plasma membrane	Hjv	IDA		Rat	PMID:16932966|RGD:1599495
Cellular Component	GO:0070724	BMP receptor complex	HJV	IDA		Human	PMID:16604073
Cellular Component	GO:0009986	cell surface	Hjv	IDA		Mouse	PMID:14749425
Cellular Component	GO:0005615	extracellular space	HJV	IDA		Human	PMID:17938254
Cellular Component	GO:0005615	extracellular space	HJV	IDA		Human	PMID:25156943
Cellular Component	GO:0005615	extracellular space	Hjv	IDA		Mouse	PMID:14749425
Cellular Component	GO:0005615	extracellular space	Hjv	IDA		Mouse	PMID:20065295
Cellular Component	GO:1990712	HFE-transferrin receptor complex	HJV	IDA		Human	PMID:22728873
Cellular Component	GO:0005886	plasma membrane	HJV	IDA		Human	PMID:16075058
Cellular Component	GO:0005886	plasma membrane	HJV	IDA		Human	PMID:17938254
Cellular Component	GO:0098797	plasma membrane protein complex	HJV	IDA		Human	PMID:18335997
Biological Process	GO:0032924	activin receptor signaling pathway	HJV	IGI	UniProtKB:P27037	Human	PMID:18326817
Biological Process	GO:0030509	BMP signaling pathway	HJV	IMP		Human	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	HJV	IGI	UniProtKB:P12643	Human	PMID:18326817
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:88180	Mouse	PMID:19751239
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:88177	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:1338938	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:107191	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:88177	Mouse	PMID:19751239
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:24409331
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:1321394	Mouse	PMID:19751239
Biological Process	GO:0030509	BMP signaling pathway	Hjv	IGI	MGI:MGI:109452	Mouse	PMID:16604073
Biological Process	GO:0071773	cellular response to BMP stimulus	HJV	IMP		Human	PMID:16604073
Biological Process	GO:0006879	intracellular iron ion homeostasis	Hjv	IMP		Mouse	MGI:MGI:5644209|PMID:25860887
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	HJV	IDA		Human	PMID:16075058
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	HJV	IGI	UniProtKB:Q92859	Human	PMID:16075058
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:19751239
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:24409331
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hjv	IMP	MGI:MGI:3587747	Mouse	PMID:22960056
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hjv	IMP	MGI:MGI:3587747	Mouse	PMID:16075058
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Hjv	IGI	MGI:MGI:88177	Mouse	PMID:20065295
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hjv	IMP		Mouse	MGI:MGI:5644209|PMID:25860887
Biological Process	GO:0030903	notochord development	hjv	IMP	ZFIN:ZDB-MRPHLNO-110301-7	Zfish	PMID:21283739
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HJV	IDA		Human	PMID:16604073
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HJV	IDA		Human	PMID:18326817
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hjv	IMP		Mouse	MGI:MGI:5644209|PMID:25860887
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hjv	IDA		Mouse	PMID:18997172
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:19751239
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hjv	IGI	MGI:MGI:88177	Mouse	PMID:16604073
Biological Process	GO:0016540	protein autoprocessing	HJV	IMP		Human	PMID:18335997
Biological Process	GO:0061053	somite development	hjv	IMP	ZFIN:ZDB-MRPHLNO-110301-7	Zfish	PMID:21283739
Biological Process	GO:0006366	transcription by RNA polymerase II	Hjv	IMP	MGI:MGI:3587746	Mouse	PMID:19751239
Biological Process	GO:0006366	transcription by RNA polymerase II	Hjv	IDA		Mouse	PMID:18997172

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern