Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HINT1
  • Mouse genes Hint1
  • Rat genes Hint1,Hint1-ps1
  • Zfish genes hint1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hint1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IMP		Human	PMID:16835243
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IDA		Human	PMID:17217311
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IMP		Human	PMID:17337452
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IMP		Human	PMID:23614568
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IMP		Human	PMID:28691797
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IMP		Human	PMID:29787766
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	HINT1	IDA		Human	PMID:31990367
Molecular Function	GO:0016929	deSUMOylase activity	HINT1	IMP		Human	PMID:31088288
Molecular Function	GO:0016929	deSUMOylase activity	Hint1	IDA		Mouse	MGI:MGI:6457166|PMID:31088288
Molecular Function	GO:0016787	hydrolase activity	HINT1	IDA		Human	PMID:16835243
Molecular Function	GO:0005515	protein binding	HINT1	IPI	UniProtKB:P50613	Human	PMID:10958787
Molecular Function	GO:0005515	protein binding	HINT1	IPI	UniProtKB:Q8N684-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hint1	IPI	UniProtKB:P0DP26|UniProtKB:P61957|UniProtKB:P63166|UniProtKB:Q9QZB0|UniProtKB:Q9WTS4	Mouse	MGI:MGI:6457166|PMID:31088288
Cellular Component	GO:0005737	cytoplasm	HINT1	IDA		Human	PMID:10958787
Cellular Component	GO:0005737	cytoplasm	HINT1	IDA		Human	PMID:8812426
Cellular Component	GO:0005829	cytosol	HINT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	HINT1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	HINT1	HDA		Human	PMID:20458337
Cellular Component	GO:0000118	histone deacetylase complex	HINT1	IDA		Human	PMID:16835243
Cellular Component	GO:0005654	nucleoplasm	HINT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HINT1	IDA		Human	PMID:10958787
Cellular Component	GO:0005634	nucleus	HINT1	IDA		Human	PMID:9770345
Cellular Component	GO:0005634	nucleus	Hint1	IDA		Mouse	PMID:9770345
Cellular Component	GO:0005886	plasma membrane	HINT1	IDA		Human	GO_REF:0000052
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	Hint1-ps1	IMP		Rat	PMID:12871960|RGD:724652
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	HINT1	IMP		Human	PMID:16835243
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	Hint1	IMP		Mouse	MGI:MGI:5512789|PMID:23576580
Biological Process	GO:0016926	protein desumoylation	HINT1	IMP		Human	PMID:31088288
Biological Process	GO:0016926	protein desumoylation	Hint1	IMP		Mouse	MGI:MGI:6457166|PMID:31088288
Biological Process	GO:0009154	purine ribonucleotide catabolic process	HINT1	IDA		Human	PMID:16835243
Biological Process	GO:0006355	regulation of DNA-templated transcription	HINT1	IMP		Human	PMID:16835243

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern