Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIKESHI
  • Mouse genes Hikeshi
  • Rat genes Hikeshi
  • Zfish genes hikeshi
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hikeshi

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030544	Hsp70 protein binding	HIKESHI	IDA		Human	PMID:22541429
Molecular Function	GO:0030544	Hsp70 protein binding	HIKESHI	IDA		Human	PMID:25760597
Molecular Function	GO:0030544	Hsp70 protein binding	HIKESHI	IPI	UniProtKB:P11142	Human	PMID:25760597
Molecular Function	GO:0060090	molecular adaptor activity	HIKESHI	IDA		Human	PMID:25760597
Molecular Function	GO:0061608	nuclear import signal receptor activity	HIKESHI	IDA		Human	PMID:22541429
Molecular Function	GO:0005515	protein binding	HIKESHI	IPI	UniProtKB:O94929-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIKESHI	IPI	UniProtKB:P32243-2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Hikeshi	IDA		Mouse	PMID:16157679
Cellular Component	GO:0005829	cytosol	HIKESHI	IDA		Human	PMID:22541429
Cellular Component	GO:0016604	nuclear body	HIKESHI	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	HIKESHI	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HIKESHI	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HIKESHI	IDA		Human	PMID:22541429
Biological Process	GO:0034605	cellular response to heat	HIKESHI	IDA		Human	PMID:22541429
Biological Process	GO:0007030	Golgi organization	Hikeshi	IMP	MGI:MGI:2449650	Mouse	PMID:16157679
Biological Process	GO:0030324	lung development	Hikeshi	IMP	MGI:MGI:2449650	Mouse	PMID:16157679
Biological Process	GO:0006606	protein import into nucleus	HIKESHI	IDA		Human	PMID:22541429
Biological Process	GO:0015031	protein transport	HIKESHI	IDA		Human	PMID:22541429

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern