Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCST
  • Mouse genes Hcst
  • Rat genes Hcst
  • Zfish genes hcst
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hcst

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043548	phosphatidylinositol 3-kinase binding	HCST	IDA		Human	PMID:10426994
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:P26718	Human	PMID:10426994
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:A0A0K2S4Q6	Human	PMID:26221034
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:O95772	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCST	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hcst	IPI	UniProtKB:Q9R007	Mouse	MGI:MGI:5009374|PMID:19074552
Molecular Function	GO:0005515	protein binding	Hcst	IPI	UniProtKB:O54885|UniProtKB:Q9R007	Mouse	MGI:MGI:3839503|PMID:19251634
Molecular Function	GO:0005515	protein binding	Hcst	IPI	PR:O54709-1	Mouse	PMID:12426565
Molecular Function	GO:0005515	protein binding	Hcst	IPI	PR:Q7TSN2	Mouse	PMID:12893283
Molecular Function	GO:0005102	signaling receptor binding	HCST	IPI	UniProtKB:O54709-1	Human	PMID:15294961
Molecular Function	GO:0005102	signaling receptor binding	HCST	IPI	UniProtKB:O54709-2	Human	PMID:15294961
Molecular Function	GO:0005102	signaling receptor binding	HCST	IPI	UniProtKB:P26718	Human	PMID:15294961
Cellular Component	GO:0009986	cell surface	HCST	IDA		Human	PMID:10426994
Cellular Component	GO:0009986	cell surface	HCST	IDA		Human	PMID:15294961
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	HCST	IDA		Human	PMID:10426994
Biological Process	GO:0006468	protein phosphorylation	HCST	IGI	UniProtKB:P27986|UniProtKB:P31749	Human	PMID:10528161

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern