Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCFC2
  • Mouse genes Hcfc2
  • Rat genes Hcfc2
  • Zfish genes hcfc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hcfc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HCFC2	IPI	UniProtKB:Q8IVD9	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	HCFC2	IPI	UniProtKB:Q8IVD9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Hcfc2	IPI	UniProtKB:Q69ZR9	Mouse	PMID:31112734
Cellular Component	GO:0005737	cytoplasm	HCFC2	IDA		Human	PMID:10196288
Cellular Component	GO:0005829	cytosol	HCFC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071339	MLL1 complex	HCFC2	IPI		Human	PMID:23508102
Cellular Component	GO:0044665	MLL1/2 complex	HCFC2	IPI		Human	PMID:23508102
Cellular Component	GO:0016604	nuclear body	HCFC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HCFC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HCFC2	IDA		Human	PMID:10196288
Cellular Component	GO:0005886	plasma membrane	HCFC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048188	Set1C/COMPASS complex	HCFC2	IPI		Human	PMID:23508102
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hcfc2	IMP		Rat	PMID:21909281|RGD:8553379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern