Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C5
  • Mouse genes Hc
  • Rat genes
  • Zfish genes c5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q03591	Human	PMID:19528535
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q91132	Human	PMID:21217642
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q96BA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:O14524-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:P23276	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q68DC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q8N4V1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q8N743	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C5	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	C5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	C5	HDA		Human	PMID:23533145
Cellular Component	GO:0005579	membrane attack complex	C5	IDA		Human	PMID:22832194
Biological Process	GO:0032835	glomerulus development	Hc	IGI		Mouse	PMID:16769899
Biological Process	GO:0001701	in utero embryonic development	Hc	IGI	MGI:MGI:88513	Mouse	PMID:18947875
Biological Process	GO:0090594	inflammatory response to wounding	Hc	IGI		Mouse	PMID:21148255
Biological Process	GO:0001822	kidney development	Hc	IGI		Mouse	PMID:16769899
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	C5	IDA		Human	PMID:14566334
Biological Process	GO:0001780	neutrophil homeostasis	Hc	IGI		Mouse	PMID:16769899
Biological Process	GO:0045766	positive regulation of angiogenesis	Hc	IMP		Mouse	MGI:MGI:3617287|PMID:16452172
Biological Process	GO:0032722	positive regulation of chemokine production	C5	IDA		Human	PMID:14566334
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	C5	IDA		Human	PMID:14566334
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	C5	IDA		Human	PMID:16452172

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern