Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HBS1L
  • Mouse genes Hbs1l
  • Rat genes Hbs1l
  • Zfish genes hbs1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hbs1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HBS1L	IPI	UniProtKB:Q9BRX2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HBS1L	IPI	UniProtKB:Q9BRX2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hbs1l	IPI	UniProtKB:Q80X73	Mouse	MGI:MGI:5574482|PMID:25061210
Cellular Component	GO:0000177	cytoplasmic exosome (RNase complex)	hbs1l	IPI		Zfish	PMID:33600438
Cellular Component	GO:0070062	extracellular exosome	HBS1L	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	HBS1L	HDA		Human	PMID:19946888
Biological Process	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	hbs1l	IMP	ZFIN:ZDB-GENO-230125-3	Zfish	PMID:33600438

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern