Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HASPIN
  • Mouse genes Haspin
  • Rat genes Haspin
  • Zfish genes haspin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Haspin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	HASPIN	IDA		Human	PMID:11228240
Molecular Function	GO:0005524	ATP binding	Haspin	IDA		Mouse	MGI:MGI:1338645|PMID:10358056
Molecular Function	GO:0003677	DNA binding	Haspin	IDA		Mouse	PMID:10358056
Molecular Function	GO:0072354	histone H3T3 kinase activity	HASPIN	IMP		Human	PMID:15681610
Molecular Function	GO:0035173	histone kinase activity	Haspin	IMP		Mouse	PMID:25645018
Molecular Function	GO:0005515	protein binding	HASPIN	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	HASPIN	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HASPIN	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0004672	protein kinase activity	HASPIN	IDA		Human	PMID:11228240
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Haspin	IDA		Mouse	PMID:10358056
Cellular Component	GO:0005813	centrosome	HASPIN	IDA		Human	PMID:11228240
Cellular Component	GO:0001673	male germ cell nucleus	Haspin	IDA		Mouse	PMID:10358056
Cellular Component	GO:0005654	nucleoplasm	HASPIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HASPIN	IDA		Human	PMID:11228240
Cellular Component	GO:0005634	nucleus	HASPIN	IDA		Human	PMID:15681610
Cellular Component	GO:0005634	nucleus	Haspin	IDA		Mouse	MGI:MGI:1338645|PMID:10358056
Cellular Component	GO:0005819	spindle	HASPIN	IDA		Human	PMID:15681610
Biological Process	GO:0070192	chromosome organization involved in meiotic cell cycle	Haspin	IMP		Mouse	PMID:25645018
Biological Process	GO:0010467	gene expression	Haspin	IMP		Mouse	PMID:25645018
Biological Process	GO:0045143	homologous chromosome segregation	Haspin	IMP		Mouse	PMID:25645018
Biological Process	GO:0035556	intracellular signal transduction	HASPIN	IDA		Human	PMID:11228240
Biological Process	GO:0035556	intracellular signal transduction	Haspin	IDA		Mouse	MGI:MGI:1338645|PMID:10358056
Biological Process	GO:1903046	meiotic cell cycle process	Haspin	IMP		Mouse	PMID:25645018
Biological Process	GO:0007132	meiotic metaphase I	Haspin	IMP		Mouse	PMID:25645018
Biological Process	GO:0007064	mitotic sister chromatid cohesion	HASPIN	IMP		Human	PMID:20705812
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	HASPIN	IMP		Human	PMID:23071153
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Haspin	IDA		Mouse	PMID:10358056
Biological Process	GO:0071459	protein localization to chromosome, centromeric region	HASPIN	IMP		Human	PMID:20705812
Biological Process	GO:0006468	protein phosphorylation	HASPIN	IDA		Human	PMID:11228240
Biological Process	GO:0006468	protein phosphorylation	Haspin	IDA		Mouse	MGI:MGI:1338645|PMID:10358056
Biological Process	GO:0006468	protein phosphorylation	Haspin	IMP		Mouse	PMID:25645018

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern