Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HACD3
  • Mouse genes Hacd3
  • Rat genes Hacd3
  • Zfish genes hacd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hacd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	HACD3	IDA		Human	PMID:18554506
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:O95292	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q03463:PRO_0000278740	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q14318	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q9P0L0	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q9UKC9	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	HACD3	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23935497
Molecular Function	GO:0005515	protein binding	Hacd3	IPI	UniProtKB:Q13200	Mouse	MGI:MGI:5586943|PMID:25036637
Molecular Function	GO:0005515	protein binding	Hacd3	IPI	UniProtKB:P63000	Mouse	PMID:10747961
Molecular Function	GO:0102158	very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity	HACD3	IDA		Human	PMID:18554506
Cellular Component	GO:0005783	endoplasmic reticulum	HACD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	HACD3	IDA		Human	PMID:18554506
Cellular Component	GO:0005925	focal adhesion	HACD3	HDA		Human	PMID:21423176
Cellular Component	GO:0031965	nuclear membrane	HACD3	IDA		Human	GO_REF:0000052
Biological Process	GO:0030497	fatty acid elongation	HACD3	IDA		Human	PMID:18554506
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Hacd3	IDA		Mouse	PMID:10747961
Biological Process	GO:0007254	JNK cascade	Hacd3	IDA		Mouse	PMID:10747961
Biological Process	GO:0046726	positive regulation by virus of viral protein levels in host cell	HACD3	IMP		Human	PMID:18160438
Biological Process	GO:0045070	positive regulation of viral genome replication	HACD3	IMP		Human	PMID:18160438
Biological Process	GO:0007266	Rho protein signal transduction	Hacd3	IDA		Mouse	PMID:10747961
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	HACD3	IDA		Human	PMID:18554506

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern