Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GUK1
  • Mouse genes Guk1
  • Rat genes Guk1
  • Zfish genes guk1a,guk1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Guk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Guk1	IDA		Mouse	MGI:MGI:6368068|PMID:12036965
Molecular Function	GO:0004385	guanylate kinase activity	GUK1	IMP		Human	PMID:31201273
Molecular Function	GO:0004385	guanylate kinase activity	GUK1	EXP		Human	PMID:8663313
Molecular Function	GO:0004385	guanylate kinase activity	GUK1	IDA		Human	PMID:8663313
Molecular Function	GO:0004385	guanylate kinase activity	Guk1	IDA		Mouse	PMID:8663313
Molecular Function	GO:0004385	guanylate kinase activity	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Molecular Function	GO:0005515	protein binding	GUK1	IPI	UniProtKB:Q7Z3Z2	Human	PMID:29515371
Cellular Component	GO:0005829	cytosol	Guk1	IDA		Mouse	MGI:MGI:6368063|PMID:29515371
Cellular Component	GO:0005829	cytosol	Guk1	IDA		Rat	PMID:10913137|RGD:5147867
Cellular Component	GO:0001917	photoreceptor inner segment	Guk1	IDA		Mouse	MGI:MGI:6368063|PMID:29515371
Biological Process	GO:0046034	ATP metabolic process	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0046060	dATP metabolic process	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0006185	dGDP biosynthetic process	GUK1	IMP		Human	PMID:31201273
Biological Process	GO:0006185	dGDP biosynthetic process	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0046054	dGMP metabolic process	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0046711	GDP biosynthetic process	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0019673	GDP-mannose metabolic process	Guk1	IDA		Rat	PMID:10913137|RGD:5147867
Biological Process	GO:0034436	glycoprotein transport	Guk1	IDA		Rat	PMID:10913137|RGD:5147867
Biological Process	GO:0046037	GMP metabolic process	Guk1	IDA		Rat	PMID:10913137|RGD:5147867
Biological Process	GO:0016310	phosphorylation	Guk1	IDA		Rat	PMID:4307347|RGD:5147877
Biological Process	GO:0006163	purine nucleotide metabolic process	GUK1	IDA		Human	PMID:8663313
Biological Process	GO:0006163	purine nucleotide metabolic process	Guk1	IDA		Mouse	MGI:MGI:81565|PMID:8663313
Biological Process	GO:0006805	xenobiotic metabolic process	GUK1	IDA		Human	PMID:6306664

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern