Comparative GO Graph (mouse, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Gucy2d
  • Rat genes Gucy2e
  • Zfish genes gucy2f
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gucy2d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004383	guanylate cyclase activity	Gucy2e	IDA		Rat	PMID:11580282|RGD:15023466
Molecular Function	GO:0004383	guanylate cyclase activity	Gucy2e	IDA		Rat	PMID:18178149|RGD:15023485
Molecular Function	GO:0004383	guanylate cyclase activity	Gucy2e	IDA		Rat	PMID:7724600|RGD:68797
Molecular Function	GO:0004383	guanylate cyclase activity	gucy2f	IMP	ZFIN:ZDB-GENO-090716-1	Zfish	PMID:19221799
Molecular Function	GO:0016941	natriuretic peptide receptor activity	Gucy2e	IDA		Rat	PMID:18178149|RGD:15023485
Molecular Function	GO:0005549	odorant binding	Gucy2d	IMP		Mouse	MGI:MGI:3722999|PMID:17724338
Molecular Function	GO:0004984	olfactory receptor activity	Gucy2d	IMP		Mouse	MGI:MGI:3722999|PMID:17724338
Molecular Function	GO:0005515	protein binding	Gucy2e	IPI	UniProtKB:Q5PQN0	Rat	PMID:18178149|RGD:15023485
Cellular Component	GO:0016020	membrane	Gucy2e	IDA		Rat	PMID:7724600|RGD:68797
Cellular Component	GO:0097730	non-motile cilium	Gucy2e	IDA		Rat	PMID:11580282|RGD:15023466
Cellular Component	GO:0005886	plasma membrane	Gucy2e	IDA		Rat	PMID:18178149|RGD:15023485
Biological Process	GO:0006182	cGMP biosynthetic process	Gucy2e	IDA		Rat	PMID:11580282|RGD:15023466
Biological Process	GO:0003031	detection of carbon dioxide	Gucy2d	IMP		Mouse	MGI:MGI:3718797|PMID:17702944
Biological Process	GO:0050911	detection of chemical stimulus involved in sensory perception of smell	Gucy2d	IMP		Mouse	MGI:MGI:3722999|PMID:17724338
Biological Process	GO:0042048	olfactory behavior	Gucy2d	IMP		Mouse	MGI:MGI:4829725|PMID:20637621
Biological Process	GO:0008355	olfactory learning	Gucy2d	IMP		Mouse	MGI:MGI:4829725|PMID:20637621
Biological Process	GO:0035845	photoreceptor cell outer segment organization	gucy2f	IMP	ZFIN:ZDB-MRPHLNO-120926-2	Zfish	PMID:22378290
Biological Process	GO:0035845	photoreceptor cell outer segment organization	gucy2f	IMP	ZFIN:ZDB-MRPHLNO-120926-1	Zfish	PMID:22378290
Biological Process	GO:0010753	positive regulation of cGMP-mediated signaling	Gucy2d	IDA		Mouse	MGI:MGI:3722999|PMID:17724338
Biological Process	GO:0007168	receptor guanylyl cyclase signaling pathway	Gucy2e	IDA		Rat	PMID:11580282|RGD:15023466
Biological Process	GO:0007168	receptor guanylyl cyclase signaling pathway	Gucy2e	IDA		Rat	PMID:18178149|RGD:15023485
Biological Process	GO:0007608	sensory perception of smell	Gucy2d	IMP		Mouse	MGI:MGI:3722999|PMID:17724338
Biological Process	GO:0007601	visual perception	gucy2f	IMP	ZFIN:ZDB-MRPHLNO-120926-1	Zfish	PMID:22378290
Biological Process	GO:0007601	visual perception	gucy2f	IMP	ZFIN:ZDB-MRPHLNO-120926-2	Zfish	PMID:22378290

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern